Evidence map›Paper›PMID 26344055›Full record

ArticleGastroenterology2015

RETRACTED: CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure

Benjamin M Stutchfield, Daniel J Antoine, Alison C Mackinnon, Deborah J Gow, Calum C Bain, Catherine A Hawley, Michael J Hughes, Benjamin Francis, Davina Wojtacha, Tak Y Man and 10 more

RetractedOpen access · hybridAbstract readCommentRetracted Publication
In one paragraph

Article in Gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 184 citations in OpenAlex.

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  7. Fibroblasts in heterotopic ossification: mechanisms and therapeutic targets.International journal of biological sciences · 2025
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  19. Cell atlas of CClZoological research · 2023
    Article
  20. [The regulatory role and related mechanisms of macrophages in wound healing].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023
    Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors at 6 institutions in 1 country.

Benjamin M StutchfieldMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom; Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Daniel J AntoineMRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Edinburgh, Edinburgh, United Kingdom.
Alison C MackinnonMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Deborah J GowThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.
Calum C BainInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Catherine A HawleyMRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Michael J HughesDivision of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Benjamin FrancisDepartment of Biostatistics, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom.
Davina WojtachaMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Tak Y ManMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom.
James W DearNational Poisons Information Service Edinburgh, Royal Infirmary of Edinburgh, University of Edinburgh, Edinburgh, United Kingdom.
Luke R DeveyMRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Alan M MowatInstitute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
Jeffrey W PollardMRC Centre for Reproductive Health, University of Edinburgh, Edinburgh, United Kingdom.
B Kevin ParkMRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Edinburgh, Edinburgh, United Kingdom.
Stephen J JenkinsMRC Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom.
Kenneth J SimpsonDivision of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom.
David A HumeMRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, University of Edinburgh, Edinburgh, United Kingdom.
Stephen J WigmoreDivision of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, United Kingdom.
Stuart J ForbesMRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh, United Kingdom. Electronic address: stuart.forbes@ed.ac.uk.
University of Edinburgh · GBMRC Centre for Regenerative Medicine · GBUniversity of Glasgow · GBCentre for Inflammation Research · GBMRC Centre for Reproductive Health · GBUniversity of Liverpool · GB

Funding

Tumor Progression and MetastasisP01CA100324 · NCI · YESHIVA UNIVERSITY · PI CONDEELIS, JOHN S · 2003 to 2018
$30.0M
Medical Research Council G1002033Medical Research Council MR/K017047/1Medical Research Council MR/K026666/1Medical Research Council MR/K026739/1Medical Research Council MR/L006758/1Medical Research Council MR/L008076/1Medical Research Council MR/M019969/1NCI NIH HHS P01 CA100324Wellcome Trust 101067
6 · The paper itself

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/policies/article-withdrawal). This article has been retracted at the request of the authors over questions of data integrity and reproducibility. Following an investigation undertaken by the University of Liverpool into research misconduct by Dr Daniel Antoine (https://news.liverpool.ac.uk/2018/07/06/research-misconduct-update/), the remaining authors elected to reanalyze independent samples of the human serum from the patient cohorts originally studied. The human serum analysis had been undertaken by Daniel Antoine at the University of Liverpool for this manuscript (REF PMID: 26344055). The coauthors were unable to reproduce the findings of the human serum analysis (doi: https://doi.org/10.1101/2021.04.02.437789) and therefore no longer have confidence in the human data component of this manuscript. The authors requested that this paper be retracted in 2019, and the Editors of Gastroenterology agree that this manuscript should be retracted. Dr Daniel Antoine played no part in any other aspects of this manuscript, and the authors have confidence in all other data.

Indexed as

Cell TransdifferentiationColony-Stimulating FactorsAnimalsHumansImmunity, InnateLiverLiver Failure, AcuteMacrophagesMiceMice, Inbred C57BLColony-Stimulating FactorsClearanceDrug-Induced Liver DamageImmune ResponseM-CSF

Identifiers

PMID26344055
PMCPMC4672154
OpenAlexW2118363577

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.