ReviewSensors (Basel, Switzerland)2015
Label-Free Biosensor Imaging on Photonic Crystal Surfaces.
Review in Sensors (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Physically grounded deep learning-enabled gold nanoparticle localization and quantification in photonic resonator absorption microscopy for digital resolution molecular diagnostics.Biosensors & bioelectronics · 2025Article
- Hybrid Metasurface for On-Chip Enrichment and Quantification of Biological Samples.ACS applied materials & interfaces · 2025Article
- Photonic Crystal Enhanced Microscopy on a 2D Photonic Crystal Surface.Advanced materials technologies · 2025Article
- Dynamic and large field of view photonic resonator absorption microscopy for ultrasensitive digital resolution detection of nucleic acid and protein biomarkers.Biosensors & bioelectronics · 2024Article
- Photonic Sensors in Chemical and Biological Applications.Biosensors · 2022Article
- Hyperspectral imaging-based exosome microarray for rapid molecular profiling of extracellular vesicles.Lab on a chip · 2021Article
- Hyperchromatic structural color for perceptually enhanced sensing by the naked eye.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Resonant and Sensing Performance of Volume Waveguide Structures Based on Polymer Nanomaterials.Nanomaterials (Basel, Switzerland) · 2020Article
- Fluorescent Aptamer Immobilization on Inverse Colloidal Crystals.Sensors (Basel, Switzerland) · 2018Article
- Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM).Light, science & applications · 2018Article
- Multiparameter resonant imaging for studying cell interactions.Light, science & applications · 2018Article
- Emerging Cytokine Biosensors with Optical Detection Modalities and Nanomaterial-Enabled Signal Enhancement.Sensors (Basel, Switzerland) · 2017Review
- A Nanofluidic Biosensor Based on Nanoreplica Molding Photonic Crystal.Nanoscale research letters · 2016Article
- Quantitative Imaging of Cell Membrane-associated Effective Mass Density Using Photonic Crystal Enhanced Microscopy (PCEM).Progress in quantum electronics · 2016Article
- Flexible Substrate-Based Devices for Point-of-Care Diagnostics.Trends in biotechnology · 2016Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
We review the development and application of nanostructured photonic crystal surfaces and a hyperspectral reflectance imaging detection instrument which, when used together, represent a new form of optical microscopy that enables label-free, quantitative, and kinetic monitoring of biomaterial interaction with substrate surfaces. Photonic Crystal Enhanced Microscopy (PCEM) has been used to detect broad classes of materials which include dielectric nanoparticles, metal plasmonic nanoparticles, biomolecular layers, and live cells. Because PCEM does not require cytotoxic stains or photobleachable fluorescent dyes, it is especially useful for monitoring the long-term interactions of cells with extracellular matrix surfaces. PCEM is only sensitive to the attachment of cell components within ~200 nm of the photonic crystal surface, which may correspond to the region of most interest for adhesion processes that involve stem cell differentiation, chemotaxis, and metastasis. PCEM has also demonstrated sufficient sensitivity for sensing nanoparticle contrast agents that are roughly the same size as protein molecules, which may enable applications in "digital" diagnostics with single molecule sensing resolution. We will review PCEM's development history, operating principles, nanostructure design, and imaging modalities that enable tracking of optical scatterers, emitters, absorbers, and centers of dielectric permittivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.