Evidence map›Paper›PMID 26343332›Full record

Trial reportContemporary clinical trials2015

Design and rationale for a randomized controlled trial to reduce readmissions among patients with depressive symptoms.

Suzanne E Mitchell, Jessica M Martin, Katherine Krizman, Ekaterina Sadikova, Larry Culpepper, Sabrina K Stewart, Jennifer Rose Brown, Brian W Jack

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Contemporary clinical trials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Suzanne E MitchellDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States. Electronic address: suzanne.mitchell@bmc.org.
Jessica M MartinDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Katherine KrizmanDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Ekaterina SadikovaDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Larry CulpepperDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Sabrina K StewartDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Jennifer Rose BrownDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Brian W JackDepartment of Family Medicine, Boston University School of Medicine, Boston, MA, United States.
Boston University · US

Funding

Reducing Hospital Readmission Among Medical Patients with Depressive SymptomsR01HS019700 · AHRQ · BOSTON MEDICAL CENTER · PI JACK, BRIAN WILLIAM · 2012 to 2016
$2.5M
AHRQ HHS R01 HS019700
6 · The paper itself

Abstract

backgroundThe Re-Engineered Discharge (Project RED) reduces 30-day readmission rates by 30%. However, our data indicates that for patients displaying depressive symptoms during hospitalization, Project RED is less effective in preventing unplanned readmission. We aim to examine the effectiveness of RED-D, a modified brief Cognitive behavioral therapy (CBT) protocol delivered as a post-discharge extension of the Re-Engineered Discharge, in reducing 30-day readmissions rates and emergency department (ED) use as well as depressive symptoms for medical patients with comorbid depressive symptoms.

methodsThis paper details the study design and implementation of an ongoing, federally funded randomized controlled trial of our post-discharge mental health intervention, RED-D, compared to the RED plus usual care. This research has two primary objectives: (1) to determine whether RED-D delivered telephonically by a mental health professional immediately following discharge is effective in reducing hospital readmission and emergency department use for patients displaying depressive symptoms during their inpatient stay, and (2) to examine whether this approach yields a clinically significant reduction in depressive symptoms. We intend to recruit 1200 participants randomized to our intervention, RED-D (n=600), and to RED plus usual care (n=600).

conclusionsHospitalized patients with depressive symptoms are at increased risk for 30-day readmission. We aim to conduct a randomized clinical trial to evaluate the comparative effectiveness of RED-D, our post-discharge modified brief CBT intervention compared to RED alone in reducing readmissions and depressive symptoms for this at-risk population.

Indexed as

Cognitive Behavioral TherapyCooperative BehaviorDepressionEmergency Service, HospitalHumansMental Health ServicesPatient Care TeamPatient ReadmissionResearch DesignCognitive Behavioral TherapyDepressionHospital dischargeMental healthReadmissionRehospitalization

Identifiers

PMID26343332
PMCPMC4762361
OpenAlexW1793098210

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.