ArticleArchives of physical medicine and rehabilitation2016
Sensorimotor Peripheral Nerve Function and the Longitudinal Relationship With Endurance Walking in the Health, Aging and Body Composition Study.
Article in Archives of physical medicine and rehabilitation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
13 citing papers in PubMed, 24 citations in OpenAlex.
- An Exercise Intervention May Counteract the Degradation of Nerve Conduction from Age-Related Disuse.Medicine and science in sports and exercise · 2025Article
- Energetics and clinical factors for the time required to walk 400 m: The Study of Muscle, Mobility and Aging (SOMMA).Journal of the American Geriatrics Society · 2024Article
- Influence of transcutaneous electrical nerve stimulation on walking kinematics and standing balance of older adults who differ in walking speed.Experimental brain research · 2023Article
- Effects of Tai Chi and Walking Exercise on Emotional Face Recognition in Elderly People: An ERP Study.Healthcare (Basel, Switzerland) · 2022Article
- Associations of Lower Extremity Peripheral Nerve Impairment and Risk of Dementia in Black and White Older Adults.Neurology · 2022Article
- Quantitative Sensory Testing Across Chronic Pain Conditions and Use in Special Populations.Frontiers in pain research (Lausanne, Switzerland) · 2021Review
- Swallowing impairment in older adults: association with sensorimotor peripheral nerve function from the Health, Aging and Body Composition study.Aging clinical and experimental research · 2021Article
- Peripheral Nerve Impairment and Recurrent Falls Among Women: Results From the Study of Women's Health Across the Nation.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- VSA-3000: A Quantitative Vibration Sensation Testing Device for Patients With Central Nervous System Injury.Frontiers in neurology · 2020Article
- Article
- Chronic kidney disease and peripheral nerve function in the Health, Aging and Body Composition Study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019Article
- Relationship between sensorimotor peripheral nerve function and indicators of cardiovascular autonomic function in older adults from the Health, Aging and Body Composition Study.Experimental gerontology · 2017Article
- Age-Related Change in Mobility: Perspectives From Life Course Epidemiology and Geroscience.The journals of gerontology. Series A, Biological sciences and medical sciences · 2016Review
Corrections and comments
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Authors and funding
16 authors at 8 institutions in 2 countries.
Funding
Abstract
objectivesTo determine whether lower extremity sensorimotor peripheral nerve deficits are associated with reduced walking endurance in older adults.
designProspective cohort study with 6 years of follow-up.
settingTwo university research clinics.
participantsCommunity-dwelling older adults enrolled in the Health, Aging and Body Composition Study from the 2000-2001 annual clinical examination (N=2393; mean age ± SD, 76.5±2.9y; 48.2% men; 38.2% black) and a subset with longitudinal data (n=1178).
interventionsNot applicable.
main outcome measuresParticipants underwent peripheral nerve function examination in 2000-2001, including peroneal motor nerve conduction amplitude and velocity, vibration perception threshold, and monofilament testing. Symptoms of lower extremity peripheral neuropathy included numbness or tingling and sudden stabbing, burning, pain, or aches in the feet or legs. The Long Distance Corridor Walk (LDCW) (400 m) was administered in 2000-2001 and every 2 years afterward for 6 years to assess endurance walking performance over time.
resultsIn separate, fully adjusted linear mixed models, poor vibration threshold (>130 μm), 10-g and 1.4-g monofilament insensitivity were each associated with a slower 400-m walk completion time (16.0 s, 14.4s, and 6.9 s slower, respectively; P<.05 for each). Poor motor amplitude (<1 mV), poor vibration perception threshold, and 10-g monofilament insensitivity were related to greater slowing per year (4.7, 4.2, and 3.8 additional seconds per year, respectively; P<.05), although poor motor amplitude was not associated with initial completion time.
conclusionsPoorer sensorimotor peripheral nerve function is related to slower endurance walking and greater slowing longitudinally. Interventions to reduce the burden of sensorimotor peripheral nerve function impairments should be considered to help older adults maintain walking endurance-a critical component for remaining independent in the community.
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Registered trials
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