ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016
Port catheter versus peripherally inserted central catheter for postoperative chemotherapy in early breast cancer: a retrospective analysis of 448 patients.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02095743 (Phase II Randomised Study Comparing the Tolerance of PICC Line), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Phase II Randomised Study Comparing the Tolerance of PICC Line (Peripherally Inserted Central Catheter) and Implanted Port for Adjuvant Chemotherapy in HER2-negative Early Breast Cancer
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Implantable Ports vs Peripherally Inserted Central Catheters in Breast Cancer Chemotherapy: A Comprehensive Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2025Pooled it
- [Clinical Practice and Quality Control Guidelines for Totally Implantable Venous Access Ports in Cancer Patients (2024)].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Guideline
- Peripherally inserted central catheters versus implantable port catheters for cancer patients: a meta-analysis.Frontiers in oncology · 2023Pooled it
- Peripherally Inserted Central Venous Catheters (PICC) versus totally implantable venous access device (PORT) for chemotherapy administration: a meta-analysis on gynecological cancer patients.Acta bio-medica : Atenei Parmensis · 2021Pooled it
- Applicability of TIVAP versus PICC in non-hematological malignancies patients: A meta-analysis and systematic review.PloS one · 2021Pooled it
- The risk of bloodstream infection associated with totally implantable venous access ports in cancer patient: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Pooled it
- [The role of central vascular access in the management of patients receiving chemotherapy for non-hematological malignant tumors: PICC line versus implantable Ports].The Pan African medical journal · 2026Trial
- Hot Compress with Chinese Herbal Salt Packets Reducing PICC Catheter Complications: A Randomized Controlled Trial.Chinese journal of integrative medicine · 2018Trial
- Peripherally inserted central catheters versus implanted port catheters in patients with breast cancer: aBJA open · 2025Article
- Uncertainty affects cancer-related fatigue among breast cancer women undergoing peripherally inserted central catheter chemotherapy: the chain mediating role of psychological resilience and self-care.BMC women's health · 2024Article
- Observational
- An Information-Based Nursing Quality Evaluation Model of Daily PICC Work in Outpatient Clinics.Contrast media & molecular imaging · 2022Article
- Safety of immediate use of totally implantable venous access ports in adult patients with cancer: a retrospective single-center study.Korean journal of clinical oncology · 2021Article
- Application of continuous nursing intervention for patients with PICC catheterization undergoing tumor chemotherapy.American journal of translational research · 2021Article
- Tailored approach to the choice of long-term vascular access in breast cancer patients.PloS one · 2021Article
- Article
- Late complications associated with totally implantable venous access port implantation via the internal jugular vein.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Article
- Predicting Catheter-Related Thrombosis in Colorectal Cancer Patients Using Clinical Features in 730 Patients.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/HemostasisArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe aimed to compare the complication rate between port catheters (PC) and peripherally inserted central catheters (PICC) for the administration of postoperative chemotherapy for breast cancer.
methodsAll patients treated from January 2010 to August 2012 at the Centre Henri Becquerel for early breast cancer requiring postoperative chemotherapy were retrospectively screened. The primary endpoint was the occurrence of a major complication related to the central venous catheter. Major complications were defined as any grade 3 event according to CTCAE 4.0, delay in chemotherapy >7 days, change of the device, life-threatening event, event requiring a hospitalization, or a prolongation of hospitalization.
resultsA total of 448 patients were included; 290 had a PC and 158 a PICC. Overall, 31 major complications related to the central venous catheter were observed: 13 for patients with a PC (4.5%) and 18 for patients with a PICC (11.4%). In univariate analysis, having a PICC was the only factor significantly associated with a higher risk of major complications (HR = 2.83, p = 0.0027). We observed a trend for a higher risk of major complications for patients older than 60 years or with BMI >25 (p = 0.06). In multivariate analysis, having a PICC was the only predictive factor of major complications (HR = 2.89, p = 0.004).
conclusionsIn univariate and multivariate analysis, having a PICC instead of a PC was the only predictive factor of device-related major complication. If confirmed prospectively by the NCT02095743 ongoing trial, this result might modify the management of adjuvant chemotherapy administration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.