SynthesisClinical neurology and neurosurgery2015
Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature.
Synthesis in Clinical neurology and neurosurgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Surgical strategies and long-term survival for third ventricle chordoid gliomas: a systematic review and clinical algorithm.Neurosurgical review · 2026Pooled it
- Chordoid glioma of the third ventricle: case report of the first successful surgical treatment in Vietnam.International journal of surgery case reports · 2026Article
- Chordoid glioma of right lateral ventricle in young male: a case report.Annals of medicine and surgery (2012) · 2025Article
- Adjuvant radiotherapy treatment of chordoid glioma: a case report with a literature review.Frontiers in oncology · 2025Article
- Pediatric CNS tumors and 2021 WHO classification: what do oncologists need from pathologists?Frontiers in molecular neuroscience · 2024Review
- Pediatric diencephalic tumors: a constellation of entities and management modalities.Frontiers in oncology · 2023Review
- Endoscope-assisted Trans-lamina Terminalis Resection of Chordoid Glioma at the Third Ventricle: A Case Report.NMC case report journal · 2023Article
- Benign Glioma.Advances in experimental medicine and biology · 2023Article
- Occurrence of Chordoid Glioma With Sodium Ion Metabolism Disorder 5 Years After Meningioma Surgery and Whole-Exome Sequencing: A Case Report and Literature Review.Frontiers in genetics · 2021Article
- One of a kind-chordoid glioma in the fourth ventricle: a case report and literature review.Acta radiologica open · 2020Article
- Prognostic factors of patients with Gliomas - an analysis on 335 patients with Glioblastoma and other forms of Gliomas.BMC cancer · 2020Article
- Chordoid Glioma of the Third Ventricle: A Case Report and a Treatment Strategy to This Rare Tumor.Frontiers in oncology · 2020Article
- Sellar and Parasellar Pain Syndromes.Current pain and headache reports · 2019Review
- Demographic Variation in the Frequency of Gliomas in Florida.Medicina (Kaunas, Lithuania) · 2019Article
- Analysis of the Factors Affecting the Prognosis of Glioma Patients.Open medicine (Warsaw, Poland) · 2019Article
- A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle.Nature communications · 2018Article
- Usefulness of neuroimaging and immunohistochemical study for accurate diagnosis of chordoid glioma of the third ventricle: A case report and review of the literature.Surgical neurology international · 2018Article
- Suprasellar chordoid glioma: a report of two cases.Archives of endocrinology and metabolism · 2018Article
- Clinicopathological analysis of HOXD4 expression in diffuse gliomas and its correlation withOncotarget · 2017Article
- Disparities in Brain Cancer in the United States: A Literature Review of Gliomas.Medical sciences (Basel, Switzerland) · 2017Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveChordoid gliomas (CG) are rare neoplasms which frequently arise within the third ventricle. Surgery remains the mainstay treatment for CG. The present study comprehensively reviews all reported cases of CG within the literature in order to identify risk factors for surgical complications and tumor recurrence.
methodsA comprehensive search on MEDLINE (OVID and PubMed), Scopus, Embase, and Web of Science was conducted following PRISMA guidelines to identify all reported cases of CG.
resultsA total of 81 patients met the study criteria which comprised of 33 males and 48 females. Median age at diagnosis was 48 years with a range from 5 to 72 years, and mean tumor size was 3.1cm. Biopsy, subtotal resection (STR), and gross total resection (GTR) were achieved in 8, 34, and 33 patients, respectively, with six cases not reporting extent of resection (EOR). Thirteen patients underwent adjuvant radiotherapy. Postoperative complications were noted in 30 cases (37%), with new onset diabetes insipidus being the most common. Postoperative morbidity was not associated with age, tumor size, or extent of resection. A trans-lamina terminalis approach demonstrated a strong trend towards decreased overall rates of postoperative morbidity compared to other approaches (p=0.051). GTR was associated with improved progression-free survival (PFS; p=0.028), while adjuvant radiotherapy, age, tumor size and proliferative index were not predictive of patient outcomes.
conclusionGTR should be the primary goal for the management of CG, as it is associated with improved rates of tumor control without an increased rate of postoperative complications. Surgical approach was a stronger predictor of complication rates than extent of resection. Morbidity remains high, and future studies to further elaborate on factors predictive of postoperative complications are critical.
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