Evidence map›Paper›PMID 26342172›Full record

ArticleJournal of affective disorders2015

Psychometric properties and factor structure of the General Health Questionnaire as a screening tool for anxiety and depressive symptoms in a multi-national study of young adults.

Bizu Gelaye, Mahlet G Tadesse, Vitool Lohsoonthorn, Somrat Lertmeharit, Wipawan C Pensuksan, Sixto E Sanchez, Seblewengel Lemma, Yemane Berhane, Juan Carlos Vélez, Clarita Barbosa and 2 more

Abstract readEvaluation Study
In one paragraph

Article in Journal of affective disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Bizu GelayeDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States. Electronic address: bgelaye@hsph.harvard.edu.
Mahlet G TadesseDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States; Department of Mathematics & Statistics, Georgetown University, Washington, DC, United States.
Vitool LohsoonthornDepartment of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Somrat LertmeharitDepartment of Preventive and Social Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Wipawan C PensuksanSchool of Nursing, Walailak University, Nakhon Si Thammarat, Thailand.
Sixto E SanchezPeruana de Ciencias Aplicadas, Lima, Peru.
Seblewengel LemmaAddis Continental Institute of Public Health, Addis Ababa, Ethiopia.
Yemane BerhaneAddis Continental Institute of Public Health, Addis Ababa, Ethiopia.
Juan Carlos VélezCentro de Rehabilitación Club de Leones Cruz del Sur, Punta Arenas, Chile.
Clarita BarbosaCentro de Rehabilitación Club de Leones Cruz del Sur, Punta Arenas, Chile.
Asterio AnderadeCentro de Rehabilitación Club de Leones Cruz del Sur, Punta Arenas, Chile.
Michelle A WilliamsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Fundación Chile · CLHarvard University · USAddis Continental Institute of Public Health · ETChulalongkorn University · THPeruvian University of Applied Sciences · PEWalailak University · TH

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
NIMHD NIH HHS T37 MD001449NIMHD NIH HHS T37-MD001449
6 · The paper itself

Abstract

backgroundGlobally, common psychiatric disorders such as depression and anxiety are among the leading causes of morbidity and mortality. The 12-item General Health Questionnaire (GHQ-12) is a widely used questionnaire for screening or detecting common psychiatric disorders. The purpose of this study was to examine the reliability, construct validity and factor structure of the GHQ-12 in a large sample of African, Asian and South American young adults.

methodsA cross-sectional study was conducted among 9077 undergraduate students from Chile, Ethiopia, Peru and Thailand. Students aged 18-35 years were invited to complete a self-administered questionnaire that collected information about lifestyle, demographics, and GHQ-12. In each country, the construct validity and factorial structures of the GHQ-12 questionnaire were tested through exploratory and confirmatory factor analyses (EFA and CFA).

resultsOverall the GHQ-12 items showed good internal consistency across all countries as reflected by the Cronbach's alpha: Chile (0.86), Ethiopia (0.83), Peru (0.85), and Thailand (0.82). Results from EFA showed that the GHQ-12 had a two-factor solution in Chile, Ethiopia and Thailand, although a three-factor solution was found in Peru. These findings were corroborated by CFA. Indicators of goodness of fit, comparative fit index (CFI), root mean square error of approximation (RMSEA), and standardized root mean squared residual, were all in acceptable ranges across study sites. The CFI values for Chile, Ethiopia, Peru and Thailand were 0.964, 0.951, 0.949, and 0.931, respectively. The corresponding RMSEA values were 0.051, 0.050, 0.059, and 0.059.

conclusionOverall, we documented cross-cultural comparability of the GHQ-12 for assessing common psychiatric disorders such as symptoms of depressive and anxiety disorders among young adults. Although the GHQ-12 is typically used as single-factor questionnaire, the results of our EFA and CFA revealed the multi- dimensionality of the scale. Future studies are needed to further evaluate the specific cut points for assessing each component within the multiple factors.

Indexed as

Health StatusAdolescentAdultAnxietyChileCross-Cultural ComparisonCross-Sectional StudiesDepressionEthiopiaFactor Analysis, StatisticalFemaleHumansMaleMass ScreeningMental HealthPeruCommon psychiatric disordersConfirmatory factor analysisExploratory factor analysisFactor structureGHQ-12

Identifiers

PMID26342172
PMCPMC4587303
OpenAlexW2141501478

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.