Evidence map›Paper›PMID 26342143›Full record

ReviewCurrent opinion in structural biology2015

Insights into the structure and function of membrane-integrated processive glycosyltransferases.

Yunchen Bi, Caitlin Hubbard, Pallinti Purushotham, Jochen Zimmer

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in structural biology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Exopolysaccharide Biosynthesis inInternational journal of molecular sciences · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Cell Energy Metabolism and Hyaluronan Synthesis.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2021
    Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yunchen BiCenter for Membrane Biology, Department of Molecular Physiology and Biological Physics, University of Virginia, 480 Ray C. Hunt Dr., Charlottesville, VA 22908, United States.
Caitlin HubbardCenter for Membrane Biology, Department of Molecular Physiology and Biological Physics, University of Virginia, 480 Ray C. Hunt Dr., Charlottesville, VA 22908, United States.
Pallinti PurushothamCenter for Membrane Biology, Department of Molecular Physiology and Biological Physics, University of Virginia, 480 Ray C. Hunt Dr., Charlottesville, VA 22908, United States.
Jochen ZimmerCenter for Membrane Biology, Department of Molecular Physiology and Biological Physics, University of Virginia, 480 Ray C. Hunt Dr., Charlottesville, VA 22908, United States. Electronic address: jochen_zimmer@virginia.edu.
University of Virginia · US

Funding

TRAINING IN CELL AND MOLECULAR BIOLOGYT32GM008136 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI STUKENBERG, P. TODD · 1985 to 2020
$8.5M
Molecular Biology of Hyaluronan BiosynthesisR01GM110143 · NIGMS · UNIVERSITY OF VIRGINIA · PI ZIMMER, JOCHEN · 2015 to 2018
$1.1M
NIGMS NIH HHS 1R01GM110143NIGMS NIH HHS R01 GM110143NIGMS NIH HHS T32 GM008136
6 · The paper itself

Abstract

Complex carbohydrates perform essential functions in life, including energy storage, cell signaling, protein targeting, quality control, as well as supporting cell structure and stability. Extracellular polysaccharides (EPS) represent mainly structural polymers and are found in essentially all kingdoms of life. For example, EPS are important biofilm and capsule components in bacteria, represent major constituents in cell walls of fungi, algae, arthropods and plants, and modulate the extracellular matrix in vertebrates. Different mechanisms evolved by which EPS are synthesized. Here, we review the structures and functions of membrane-integrated processive glycosyltransferases (GTs) implicated in the synthesis and secretion of chitin, alginate, hyaluronan and poly-N-acetylglucosamine (PNAG).

Indexed as

AnimalsBiopolymersChitin SynthaseGlycosyltransferasesHumansMembrane ProteinsMolecular WeightPolysaccharidesProtein Interaction Domains and MotifsProtein Processing, Post-TranslationalStructure-Activity RelationshipBiopolymersChitin SynthaseGlycosyltransferasesMembrane ProteinsPolysaccharides

Identifiers

PMID26342143
PMCPMC4684724
OpenAlexW1226975619

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.