Evidence map›Paper›PMID 26342094›Full record

ArticleArchives of disease in childhood2016

Admission to hospital for bronchiolitis in England: trends over five decades, geographical variation and association with perinatal characteristics and subsequent asthma.

Christopher A Green, David Yeates, Allie Goldacre, Charles Sande, Roger C Parslow, Philip McShane, Andrew J Pollard, Michael J Goldacre

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of disease in childhood, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 3 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 3 syntheses or guidelines pooled it, 194 citations in OpenAlex.

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  11. Prevention of respiratory syncytial virus disease by immunisation.Archives of disease in childhood. Education and practice edition · 2025
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Christopher A GreenDepartment of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, UK.
David YeatesUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Allie GoldacreUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Charles SandeDepartment of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, UK.
Roger C ParslowDivision of Epidemiology and Biostatistics, University of Leeds, Leeds, UK.
Philip McShaneDivision of Epidemiology and Biostatistics, University of Leeds, Leeds, UK.
Andrew J PollardDepartment of Paediatrics, University of Oxford, and the NIHR Oxford Biomedical Research Centre, UK.
Michael J GoldacreUnit of Health-Care Epidemiology, Nuffield Department of Population Health, University of Oxford, Oxford, UK.
Oxford BioMedica (United Kingdom) · GBUniversity of Oxford · GBUniversity of Leeds · GB

Funding

Medical Research Council MR/L01629X/1
6 · The paper itself

Abstract

backgroundAdmission of infants to hospital with bronchiolitis consumes considerable healthcare resources each winter. We report an analysis of hospital admissions in England over five decades.

methodsData were analysed from the Hospital In-Patient Enquiry (HIPE, 1968-1985), Hospital Episode Statistics (HES, 1989-2011), Oxford Record Linkage Study (ORLS, 1963-2011) and Paediatric Intensive Care Audit Network (PICANet, 2003-2012). Cases were identified using International Classification of Diseases (ICD) codes in discharge records. Bronchiolitis was given a separate code in ICD9 (used in England from 1979). Geographical variation was analysed using Local Authority area boundaries. Maternal and perinatal risk factors associated with bronchiolitis and subsequent admissions for asthma were analysed using record-linkage.

resultsAll-England HIPE and HES data recorded 468 138 episodes of admission for bronchiolitis in infants aged <1 year between 1979 and 2011. In 2011 the estimated annual hospital admission rate was 46.1 (95% CI 45.6 to 46.6) per 1000 infants aged <1 year. Between 2004 and 2011 the rates rose by an average of 1.8% per year in the all-England HES data, whereas admission rates to paediatric intensive care changed little (1.3 to 1.6 per 1000 infants aged <1 year). A fivefold geographical variation in hospital admission rates was observed. Young maternal age, low social class, low birth weight and maternal smoking were among factors associated with an increased risk of hospital admission with bronchiolitis.

conclusionsHospital admissions for infants with bronchiolitis have increased substantially in recent years. However, cases requiring intensive care have changed little since 2004.

Indexed as

AdolescentAdultAsthmaBirth WeightBronchiolitisChild, PreschoolEnglandHospitalizationHumansInfantInfant, NewbornIntensive Care Units, PediatricMaternal AgeMedical Record LinkagePatient AdmissionRisk FactorsEpidemiologyGeneral PaediatricsInfectious DiseasesIntensive CareRespiratory

Identifiers

PMID26342094
PMCPMC4752648
OpenAlexW1957115089

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.