ArticleClinical journal of the American Society of Nephrology : CJASN2015
The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.
Article in Clinical journal of the American Society of Nephrology : CJASN, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06177886 (Incidence and Predictive Risk Factors of Acute Kidney Injury in Pediatric Polytrauma Patients Admitted to Assiut University Trauma Unit), which is not on this map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incidence and Predictive Risk Factors of Acute Kidney Injury in Pediatric Polytrauma Patients Admitted to Assiut University Trauma Unit: a Cross-sectional Study
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Incidence and risk factors for acute kidney injury in children with nephrotic syndrome: a meta-analysis.Frontiers in pediatrics · 2024Pooled it
- Acute kidney injury in trauma patients admitted to the ICU: a systematic review and meta-analysis.Intensive care medicine · 2019Pooled it
- Association between ABO blood groups and sepsis risk in severe burns: a retrospective cohort study.BMC infectious diseases · 2026Article
- The Impact of ABO Blood Type on Hemoglobin Decline After Total Hip Arthroplasty.Journal of clinical medicine · 2026Article
- The ultimate tradeoff: how red cell adaptations to malaria alter the host response during critical illness.American journal of physiology. Lung cellular and molecular physiology · 2023Review
- Analysis between ABO blood group and clinical outcomes in COVID-19 patients and the potential mediating role of ACE2.Frontiers in medicine · 2023Article
- The correlation between non-O blood group type and recurrent catheter-associated urinary tract infections in critically ill patients: A retrospective study.The Journal of international medical research · 2022Article
- ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29 512 patients.BMC anesthesiology · 2022Observational
- APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis.Immunity · 2021Article
- The impact of blood type on the mortality of patients with severe abdominal trauma: a multicenter observational study.Scientific reports · 2021Observational
- ABO blood types and sepsis mortality.Annals of intensive care · 2021Article
- ABO blood type: a window into the genetics of acute respiratory distress syndrome susceptibility.The Journal of clinical investigation · 2021Article
- ABO Blood Group and Outcomes in Patients with COVID-19 Admitted in the Intensive Care Unit (ICU): A Retrospective Study in a Tertiary-Level Hospital in Bangladesh.Journal of multidisciplinary healthcare · 2021Article
- Impact of Blood Type O on Mortality of Sepsis Patients: A Multicenter Retrospective Observational Study.Diagnostics (Basel, Switzerland) · 2020Article
- Relationship of body mass index, serum creatine kinase, and acute kidney injury after severe trauma.The journal of trauma and acute care surgery · 2020Article
- Incidence and epidemiology of acute kidney injury in a pediatric Malawian trauma cohort: a prospective observational study.BMC nephrology · 2020Observational
- Interleukin-37 Attenuates Lipopolysaccharide (LPS)-Induced Neonatal Acute Respiratory Distress Syndrome in Young Mice via Inhibition of Inflammation and Cell Apoptosis.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- Plasma receptor interacting protein kinase-3 levels are associated with acute respiratory distress syndrome in sepsis and trauma: a cohort study.Critical care (London, England) · 2019Article
- Acute Respiratory Distress Syndrome Phenotypes.Seminars in respiratory and critical care medicine · 2019Review
- Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma.American journal of respiratory and critical care medicine · 2019Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
objectiveABO blood types are determined by antigen modifications on glycoproteins and glycolipids and associated with altered plasma levels of inflammatory and endothelial injury markers implicated in AKI pathogenesis. We sought to determine the association of ABO blood types with AKI risk in critically ill patients with trauma or sepsis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We conducted two prospective cohort studies at an urban, academic, level I trauma center and tertiary referral center; 497 patients with trauma admitted to the surgical intensive care unit between 2005 and 2010 with an injury severity score >15 and 759 patients with severe sepsis admitted to the medical intensive care unit between 2008 and 2013 were followed for 6 days for the development of incident AKI. AKI was defined by Acute Kidney Injury Network creatinine and dialysis criteria.
resultsOf 497 patients with trauma, 134 developed AKI (27%). In multivariable analysis, blood type A was associated with higher AKI risk relative to type O among patients of European descent (n=229; adjusted risk, 0.28 versus 0.14; risk difference, 0.14; 95% confidence interval, 0.03 to 0.24; P=0.02). Of 759 patients with sepsis, AKI developed in 326 (43%). Blood type A again conferred higher AKI risk relative to type O among patients of European descent (n=437; adjusted risk, 0.53 versus 0.40; risk difference, 0.14; 95% confidence interval, 0.04 to 0.23; P=0.01). Findings were similar when analysis was restricted to those patients who did not develop acute respiratory distress syndrome or were not transfused. We did not detect a significant association between blood type and AKI risk among individuals of African descent in either cohort.
conclusionsBlood type A is independently associated with AKI risk in critically ill patients with trauma or severe sepsis of European descent, suggesting a role for ABO glycans in AKI susceptibility.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.