Evidence map›Paper›PMID 26341741›Full record

Trial reportHaematologica2015

Phase II trial of ponatinib in patients with chronic myeloid leukemia resistant to one previous tyrosine kinase inhibitor.

David Sanford, Hagop Kantarjian, Jeffrey Skinner, Elias Jabbour, Jorge Cortes

Abstract readClinical Trial, Phase IILetter
In one paragraph

Trial report in Haematologica, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David SanfordThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Hagop KantarjianThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Jeffrey SkinnerThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Elias JabbourThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA.
Jorge CortesThe University of Texas M.D. Anderson Cancer Center, Houston, TX, USA jcortes@mdanderson.org.

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672NCI NIH HHS P30 CA16672
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedDrug Resistance, NeoplasmFemaleHumansImidazolesLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMaleMiddle AgedProtein Kinase InhibitorsPyridazinesImidazolesponatinibProtein Kinase InhibitorsPyridazineschronic myeloid leukemiaphase IIponatinibresistanttyrosine kinase inhibitor

Identifiers

PMID26341741
PMCPMC4666339

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.