Evidence map›Paper›PMID 26341218›Full record

Trial reportInternal and emergency medicine2015

A simplified way for the urgent treatment of somatic pain in patients admitted to the emergency room: the SUPER algorithm.

Francesco Franceschi, Davide Marsiliani, Andrea Alesi, Maria Grazia Mancini, Veronica Ojetti, Marcello Candelli, Maurizio Gabrielli, Gabriella D'Aurizio, Emanuele Gilardi, Enrica Adducci and 2 more

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Internal and emergency medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05025228 (Analgesic Effect of Paracetamol in Patients With Femur Fracture), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05025228 completednot on this mapstarted 2019, after this paper: background citation

Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?

TypeobservationalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2019 to 2020Enrolled170ConditionsFemur FractureArmsParacetamol
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Pain Prevalence and Pain Management in a Chinese Hospital.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Francesco FranceschiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy. francesco.franceschi@rm.unicatt.it.
Davide MarsilianiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Andrea AlesiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Maria Grazia ManciniEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Veronica OjettiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Marcello CandelliEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Maurizio GabrielliEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Gabriella D'AurizioEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Emanuele GilardiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Enrica AdducciEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Rodolfo ProiettiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.
Francesco BuccellettiEmergency Department, Catholic University of Sacred Heart, Policlinico "A. Gemelli", Largo A. Gemelli, 8, 00168, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Somatic pain is one of the most frequent symptoms reported by patients presenting to the emergency department (ED), but, in spite of this, it is very often underestimated and under-treated. Moreover, pain-killers prescriptions are usually related to the medical examination, leading to a delay in its administration, thus worsening the patient's quality of life. With our study, we want to define and validate a systematic and homogeneous approach to analgesic drugs administration, testing a new therapeutic algorithm in terms of earliness, safety, and efficacy. 442 consecutive patients who accessed our ED for any kind of somatic pain were enrolled, and then randomly divided into two groups: group A follow the normal process of access to pain-control drugs, and group B follow our SUPER algorithm for early administration of drugs to relieve pain directly from triage. We excluded from the study, patients with abdominal pain referred to the surgeon, patients with headache, recent history of trauma, history of drug allergies, and life-threatening conditions or lack of cooperation. Drugs used in the study were those available in our ED, such as paracetamol, paracetamol/codeine, ketorolac-tromethamine, and tramadol-hydrochloride. Pain level, risk factors, indication, and contraindication of each drug were taken into account in our SUPER algorithm for a rapid and safe administration of it. The Verbal Numeric Scale (VNS) and the Visual Analog Scale (VAS) were used to verify the patient's health and perception of it. Only 59 patient from group A (27.1 %) received analgesic therapy (at the time of the medical examination) compared to 181 patients (100 %) of group B (p < 0.001). Group B patients, received analgesic therapy 76 min before group A subjects (p < 0.01), resulting in a significant lower VNS (7.31 ± 1.68 vs 4.75 ± 2.3; p < 0.001), and a superior VAS after discharge (54.43 ± 22.16 vs 61.30 ± 19.13; p < 0.001) compared to group A subjects. No significant differences concerning side effects were observed between group A and group B patients. Early administration of a pain-control therapy directly from triage is safe and effective, and significantly improves patients perceptions of their own health.

Indexed as

AlgorithmsEmergency Service, HospitalPain MeasurementTriageAdultAnalgesicsFemaleHumansItalyMaleMiddle AgedNociceptive PainAnalgesicsAcetaminophenEmergency DepartmentNSAIDsPain managementPain treatment

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.