ArticleBMC pediatrics2015
Factors associated with red blood cell transfusions in very-low-birth-weight preterm infants in Brazilian neonatal units.
Article in BMC pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Adverse outcomes after red blood cell transfusion in very low birth weight infants in a resource-restricted hospital.Transfusion · 2025Article
- Risk factors associated with anemia of prematurity requiring red blood cell transfusion in very low birth weight infants: a retrospective study.BMC pediatrics · 2024Article
- Banked term umbilical cord blood to meet the packed red blood cell transfusion needs of extremely-low-gestational-age neonates: a feasibility analysis.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Epidemiology, risk factors, clinical presentation and complications of late-onset neonatal sepsis among preterm neonates in Cyprus: a prospective case-control study.BMC pediatrics · 2024Article
- Predictors of Mortality in Early Neonatal Sepsis: A Single-Center Experience.Medicina (Kaunas, Lithuania) · 2023Article
- Impact of level of neonatal care on phlebotomy and blood transfusion in extremely low birthweight infants: a prospective, multicenter, observational study.Frontiers in pediatrics · 2023Article
- Can Restrictive Approach in Neonatal Transfusion Justify the Clinical Outcome?Indian journal of pediatrics · 2022Article
- Transfusion-Free Survival Predicts Severe Retinopathy in Preterm Neonates.Frontiers in pediatrics · 2022Article
- Transfusion prevention using erythropoietin, parenteral sucrose iron, and fewer phlebotomies in infants born at ≤30 weeks gestation at a high altitude center: a 10-year experience.Journal of perinatology : official journal of the California Perinatal Association · 2021Article
- Anemia of prematurity: how low is too low?Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Are single-donor red blood cell transfusions still relevant for preterm infants?Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Foetal haemoglobin, blood transfusion, and retinopathy of prematurity.Eye (London, England) · 2018Article
- Association between anemia and bronchopulmonary dysplasia in preterm infants.Scientific reports · 2016Observational
- Current Understanding of Transfusion-associated Necrotizing Enterocolitis: Review of Clinical and Experimental Studies and a Call for More Definitive Evidence.Newborn (Clarksville, Md.)Article
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20 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPreterm infants in neonatal intensive care units frequently receive red blood cells (RBC) transfusions due to the anemia of prematurity. A number of variables related to gestational age, severity of illness and transfusion practices adopted in the neonatal unit where the neonate was born may contribute to the prescription of RBC transfusions. This study aimed to analyse the frequency and factors associated with RBC transfusions in very-low-birth-weight preterm infants.
methodsA prospective cohort of 4283 preterm infants (gestational age: 29.9 ± 2.9 weeks; birth weight: 1084 ± 275 g) carried out at 16 university hospitals in Brazil between January 2009 and December 2011 was analysed. Factors associated with RBC transfusions were evaluated using univariate and multiple logistic regression analysis.
resultsA total of 2208 (51.6%) infants received RBC transfusions (variation per neonatal unit: 34.1% to 66.4%). RBC transfusions were significantly associated with gestational age (OR: -1.098; 95%CI: -1.12 to -1.04), SNAPPE II score (1.01; 1.00-1.02), apnea (1.69; 1.34-2.14), pulmonary hemorrhage (2.65; 1.74-4.031), need for oxygen at 28 days of life (1.56; 1.17-2.08), clinical sepsis (3.22; 2.55-4.05), necrotising enterocolitis (3.80; 2.26-6.41), grades III/IV intraventricular hemorrhage (1.64; 1.05-2.58), mechanical ventilation (2.27; 1.74-2.97), use of umbilical catheter (1.86; 1.35-2.57), parenteral nutrition (2.06; 1.27-3.33), >60 days of hospitalization (5.29; 4.02-6.95) and the neonatal unit where the neonate was born.
conclusionsThe frequency of RBC transfusions varied among neonatal intensive care units. Even after adjusting for adverse health conditions and therapeutic interventions, the neonatal unit continued to influence transfusion practices in very-low birth-weight infants.
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