ArticleJournal of the American Medical Directors Association2016
Remaining Life Expectancy With and Without Polypharmacy: A Register-Based Study of Swedes Aged 65 Years and Older.
Article in Journal of the American Medical Directors Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Prevalence of polypharmacy use and association with mortality: a cohort study of elderly people in Southern Brazil, 2014-2017.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2025Article
- Application of STOPP/START criteria in older patients in primary care using RStudio®.BMC geriatrics · 2024Article
- Pre-clinical Models for Geriatric Pharmacotherapy.Drugs & aging · 2024Review
- Knowledge Assessment During the Medication Process Use by Older Patients on Clinical Routine: A Pilot Study.Turkish journal of pharmaceutical sciences · 2023Article
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- Addressing the critical role of gender identity and sex in the planning, analysis, and conduct of clinical trials.Principles and practice of clinical research (2015) · 2021Article
- Prevalence of potential drug-drug interactions in outpatients of a general hospital in China: a retrospective investigation.International journal of clinical pharmacy · 2020Article
- Patterns and characteristics of polypharmacy among elderly residents in Danish nursing homes.Future science OA · 2020Article
- An Increasing Trend in the Prevalence of Polypharmacy in Sweden: A Nationwide Register-Based Study.Frontiers in pharmacology · 2020Article
- Risk Factors for Injurious Falls in Older Adults: The Role of Sex and Length of Follow-Up.Journal of the American Geriatrics Society · 2019Article
- Risk factors for polypharmacy in older adults in a primary care setting: a cross-sectional study.Clinical interventions in aging · 2018Article
- Medication Use and Fall-Related Hospital Admissions from Long-Term Care Facilities: A Hospital-Based Case-Control Study.Drugs & aging · 2017Article
- Changes in Drug Use and Polypharmacy After the Age of 90: A Longitudinal Study of the Danish 1905 Cohort.Journal of the American Geriatrics Society · 2017Article
- The Management of Geriatric and Frail HIV Patients. A 2017 Update from the Italian Guidelines for the Use of Antiretroviral Agents and the Diagnostic Clinical Management of HIV-1 Infected Persons.The Journal of frailty & agingArticle
- Impact of Clinical Pharmacist's Interventions on Potential Drug-Drug Interactions in the Cardiac Care Units of Two University Hospitals in Shiraz, South of Iran.Journal of research in pharmacy practiceArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the remaining life expectancy with and without polypharmacy for Swedish women and men aged 65 years and older.
designAge-specific prevalence of polypharmacy from the nationwide Swedish Prescribed Drug Register (SPDR) combined with life tables from Statistics Sweden was used to calculate the survival function and remaining life expectancy with and without polypharmacy according to the Sullivan method.
settingNationwide register-based study.
participantsA total of 1,347,564 individuals aged 65 years and older who had been prescribed and dispensed a drug from July 1 to September 30, 2008. MEASUREMENTS: Polypharmacy was defined as the concurrent use of 5 or more drugs.
resultsAt age 65 years, approximately 8 years of the 20 remaining years of life (41%) can be expected to be lived with polypharmacy. More than half of the remaining life expectancy will be spent with polypharmacy after the age of 75 years. Women had a longer life expectancy, but also lived more years with polypharmacy than men. DISCUSSION: Older women and men spend a considerable proportion of their lives with polypharmacy.
conclusionGiven the negative health outcomes associated with polypharmacy, efforts should be made to reduce the number of years older adults spend with polypharmacy to minimize the risk of unwanted consequences.
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