Evidence map›Paper›PMID 26340994›Full record

ArticleBMC pediatrics2015

Differences in perinatal and infant mortality in high-income countries: artifacts of birth registration or evidence of true differences?

Paromita Deb-Rinker, Juan Andrés León, Nicolas L Gilbert, Jocelyn Rouleau, Anne-Marie Nybo Andersen, Ragnheiður I Bjarnadóttir, Mika Gissler, Laust H Mortensen, Rolv Skjærven, Stein Emil Vollset and 6 more

Abstract read
In one paragraph

Article in BMC pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Definitions, terminology and standards for reporting of births and deaths in the perinatal period: International Classification of Diseases (ICD-11).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2025
    Review
  4. Article
  5. Article
  6. A new record linkage for assessing infant mortality rates in Ontario, Canada.Canadian journal of public health = Revue canadienne de sante publique · 2020
    Article
  7. Unattended Pregnancies and Perinatal Mortality in Georgia.Risk management and healthcare policy · 2020
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Perinatal health services organization for preterm births: a multinational comparison.Journal of perinatology : official journal of the California Perinatal Association · 2017
    Article
  13. Article
  14. Review
  15. Infant mortality in the United States.Journal of perinatology : official journal of the California Perinatal Association · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Paromita Deb-RinkerMaternal and Infant Health Section, Surveillance and Epidemiology Division, Centre for Chronic Disease Prevention, Public Health Agency of Canada, 785 Carling Avenue, AL 6804A, Ottawa, Ontario, K1A 0K9, Canada. Paromita.Deb-Rinker@phac-aspc.gc.ca.
Juan Andrés LeónMaternal and Infant Health Section, Surveillance and Epidemiology Division, Centre for Chronic Disease Prevention, Public Health Agency of Canada, 785 Carling Avenue, AL 6804A, Ottawa, Ontario, K1A 0K9, Canada. Juan.andres.leon@phac-aspc.gc.ca.
Nicolas L GilbertMaternal and Infant Health Section, Surveillance and Epidemiology Division, Centre for Chronic Disease Prevention, Public Health Agency of Canada, 785 Carling Avenue, AL 6804A, Ottawa, Ontario, K1A 0K9, Canada. Nicolas.Gilbert@phac-aspc.gc.ca.
Jocelyn RouleauMaternal and Infant Health Section, Surveillance and Epidemiology Division, Centre for Chronic Disease Prevention, Public Health Agency of Canada, 785 Carling Avenue, AL 6804A, Ottawa, Ontario, K1A 0K9, Canada. Jocelyn.Rouleau@phac-aspc.gc.ca.
Anne-Marie Nybo AndersenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark. amny@sund.ku.dk.
Ragnheiður I BjarnadóttirDepartment of Obstetrics and Gynecology, Landspitali, Rekjavik, Iceland. ragnhib@landspitali.is.
Mika GisslerNational Institute of Health and Welfare (THL), Helsinki, Finland. mika.gissler@thl.fi.
Laust H MortensenDepartment of Public Health, University of Copenhagen, Copenhagen, Denmark. lamo@sund.ku.dk.
Rolv SkjærvenMedical Birth Registry of Norway, University of Bergen, Bergen, Norway. Rolv.Skjarven@igs.uib.no.
Stein Emil VollsetMedical Birth Registry of Norway, University of Bergen, Bergen, Norway. Vollset@uib.no.
Xun ZhangDepartments of Pediatrics and of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada. xun.zhang@muhc.mcgill.ca.
Prakesh S ShahDepartment of Paediatrics, University of Toronto, Mount Sinai Hospital, Toronto, Ontario, Canada. PShah@mtsinai.on.ca.
Reg S SauveDepartments of Pediatrics and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada. rsauve@ucalgary.ca.
Michael S KramerDepartments of Pediatrics and of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Quebec, Canada. michael.kramer@mcgill.ca.
K S JosephDepartment of Obstetrics and Gynaecology and the School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada. kjoseph@cw.bc.ca.
Canadian Perinatal Surveillance System Public Health Agency of Canada

Funding

Canadian Institutes of Health Research
6 · The paper itself

Abstract

backgroundVariation in birth registration criteria may compromise international comparisons of fetal and infant mortality. We examined the effect of birth registration practices on fetal and infant mortality rates to determine whether observed differences in perinatal and infant mortality rates were artifacts of birth registration or reflected true differences in health status.

methodsA retrospective population-based cohort study was done using data from Canada, United States, Denmark, Finland, Iceland, Norway, and Sweden from 1995-2005. Main outcome measures included live births by gestational age and birth weight; gestational age-and birth weight-specific stillbirth rates; neonatal, post-neonatal, and cause-specific infant mortality.

resultsProportion of live births <22 weeks varied substantially: Sweden (not reported), Iceland (0.00%), Finland (0.001%), Denmark (0.01%), Norway (0.02%), Canada (0.07%) and United States (0.08%). At 22-23 weeks, neonatal mortality rates were highest in Canada (892.2 per 1000 live births), Denmark (879.3) and Iceland (1000.0), moderately high in the United States (724.1), Finland (794.3) and Norway (739.0) and low in Sweden (561.2). Stillbirth:live birth ratios at 22-23 weeks were significantly lower in the United States (79.2 stillbirths per 100 live births) and Finland (90.8) than in Canada (112.1), Iceland (176.2) and Norway (173.9). Crude neonatal mortality rates were 83% higher in Canada and 96% higher in the United States than Finland. Neonatal mortality rates among live births ≥ 28 weeks were lower in Canada and United States compared with Finland. Post-neonatal mortality rates were higher in Canada and United States than in Nordic countries.

conclusionsLive birth frequencies and stillbirth and neonatal mortality patterns at the borderline of viability are likely due to differences in birth registration practices, although true differences in maternal, fetal and infant health cannot be ruled out. This study emphasises the need for further standardisations, in order to enhance the relevance of international comparisons of infant mortality.

Indexed as

Birth CertificatesFetal MortalityInfant MortalityVital StatisticsBirth WeightCanadaGestational AgeHumansInfantInfant, NewbornRetrospective StudiesScandinavian and Nordic CountriesUnited States

Identifiers

PMID26340994
PMCPMC4560894

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.