ArticleJournal of autism and developmental disorders2016
Altered Dynamics of the fMRI Response to Faces in Individuals with Autism.
Article in Journal of autism and developmental disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prediction in Autism Spectrum Disorder: A Systematic Review of Empirical Evidence.Autism research : official journal of the International Society for Autism Research · 2021Pooled it
- Serotonin differentially modulates the temporal dynamics of the limbic response to facial emotions in male adults with and without autism spectrum disorder (ASD): a randomised placebo-controlled single-dose crossover trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2020Trial
- Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis.Journal of autism and developmental disorders · 2020Trial
- Trial
- Processing of emotional faces has unique functional and cytoarchitectural associations in those with an autism spectrum diagnosis.Journal of neurodevelopmental disorders · 2026Article
- Processing of Emotional Faces Has Unique Functional and Cytoarchitectural Associations in those with an Autism Spectrum Diagnosis.bioRxiv : the preprint server for biology · 2025Article
- Prefrontal Cortex Responses to Social Video Stimuli in Young Children with and without Autism Spectrum Disorder.Brain sciences · 2024Article
- Delineating Visual Habituation Profiles in Preschoolers with Neurofibromatosis Type 1 and Autism Spectrum Disorder: A Cross-Syndrome Study.Journal of autism and developmental disorders · 2024Article
- Sensory Gating in Neurodevelopmental Disorders: A Scoping Review.Research on child and adolescent psychopathology · 2023Article
- Trauma exposure among cannabis use disorder individuals was associated with a craving-correlated non-habituating amygdala response to aversive cues.Drug and alcohol dependence reports · 2022Article
- Brain-wide visual habituation networks in wild type and fmr1 zebrafish.Nature communications · 2022Article
- What is the Effect of Stimulus Complexity on Attention to Repeating and Changing Information in Autism?Journal of autism and developmental disorders · 2022Article
- Translational Magnetic Resonance Imaging in Autism Spectrum Disorder From the Mouse Model to Human.Frontiers in neuroscience · 2022Review
- Sustained brain response to repeated drug cues is associated with poor drug-use outcomes.Addiction biology · 2021Article
- Age- and sex-specific fear conditioning deficits in mice lacking Pcdh10, an Autism Associated Gene.Neurobiology of learning and memory · 2021Article
- Processing of expressions by individuals with autistic traits: Empathy deficit or sensory hyper-reactivity?PloS one · 2021Article
- Perceptual category learning in autism spectrum disorder: Truth and consequences.Neuroscience and biobehavioral reviews · 2020Review
- A Longitudinal Study of Local Gyrification Index in Young Boys With Autism Spectrum Disorder.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Early enhanced processing and delayed habituation to deviance sounds in autism spectrum disorder.Brain and cognition · 2018Article
- Neuron numbers increase in the human amygdala from birth to adulthood, but not in autism.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Abnormal fMRI habituation in autism spectrum disorders (ASDs) has been proposed as a critical component in social impairment. This study investigated habituation to fearful faces and houses in ASD and whether fMRI measures of brain activity discriminate between ASD and typically developing (TD) controls. Two identical fMRI runs presenting masked fearful faces, houses, and scrambled images were collected. We found significantly slower fMRI responses to fearful faces but not houses in ASD. In addition, the pattern of slow to emerge amygdala activation to faces had robust discriminability [ASD vs. TD; area under the curve (AUC) = .852, p < .001]. In contrast, habituation to houses had no predictive value (AUC = .573, p = .365). Amygdala habituation to emotional faces may be useful for quantifying risk in ASD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.