Evidence map›Paper›PMID 26340844›Full record

ArticleHeart rhythm2016

Secondhand smoke and atrial fibrillation: Data from the Health eHeart Study.

Shalini Dixit, Mark J Pletcher, Eric Vittinghoff, Kourtney Imburgia, Carol Maguire, Isaac R Whitman, Stanton A Glantz, Jeffrey E Olgin, Gregory M Marcus

Open access · greenAbstract read
In one paragraph

Article in Heart rhythm, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. European Heart Rhythm Association (EHRA)/European Association of Cardiovascular Prevention and Rehabilitation (EACPR) position paper on how to prevent atrial fibrillation endorsed by the Heart Rhythm Society (HRS) and Asia Pacific Heart Rhythm Society (APHRS).Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2017
    Guideline
  3. Guideline
  4. Article
  5. Article
  6. Review
  7. Review
  8. Secondhand Smoking and the Fetus: A Bibliometric Analysis.Medical journal of the Islamic Republic of Iran · 2023
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Thirdhand Smoke Contamination and Infant Nicotine Exposure in a Neonatal Intensive Care Unit: An Observational Study.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2021
    Observational
  15. Article
  16. Health advocacy for reducing smoking rates in Hamamatsu, Japan.Hypertension research : official journal of the Japanese Society of Hypertension · 2020
    Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shalini DixitDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California.
Mark J PletcherDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Eric VittinghoffDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Kourtney ImburgiaDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California.
Carol MaguireDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California.
Isaac R WhitmanDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California.
Stanton A GlantzDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California; Center for Tobacco Control Research and Education, University of California, San Francisco, San Francisco, California.
Jeffrey E OlginDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California.
Gregory M MarcusDivision of Cardiology(,) Department of Medicine, University of California, San Francisco, San Francisco, California. Electronic address: marcusg@medicine.ucsf.edu.
University of California, San Francisco · US

Funding

Clinical and Transtional Science InstituteKL2TR000143 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$11.9M
Clinical and Transtional Science InstituteTL1TR000144 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$643k
NCATS NIH HHS KL2 TR000143NCATS NIH HHS TL1 TR000144NCATS NIH HHS TL1TR000144
6 · The paper itself

Abstract

backgroundCigarette smoking is a risk factor for atrial fibrillation (AF), but whether secondhand smoke (SHS) impacts the risk of AF remains unknown.

objectiveTo determine if SHS exposure is associated with an increased risk of AF.

methodsWe performed a cross-sectional analysis of data from participants enrolled in the Health eHeart Study, an internet-based, longitudinal cardiovascular cohort study, who completed baseline SHS exposure and medical conditions questionnaires. SHS was assessed through a validated 22-question survey, and prevalent AF was assessed by self-report, with validation of a subset (n = 42) by review of electronic medical records.

resultsOf 4976 participants, 593 (11.9%) reported having AF. In unadjusted analyses, patients with AF were more likely to have been exposed to SHS in utero, as a child, as an adult, at home, and at work. After multivariable adjustment for potential confounders, having had a smoking parent during gestational development (OR 1.37, 95% CI 1.08-1.73, P = .009) and residing with a smoker during childhood (OR 1.40, 95% CI 1.10-1.79, P = .007) were each significantly associated with AF. Both positive associations were more pronounced among patients without risk factors for AF (P values for interaction <.05).

conclusionsSHS exposure during gestational development and during childhood was associated with having AF later in life. This association was even stronger in the absence of established risk factors for AF. Our findings indicate that SHS in early life may be an important, potentially modifiable risk factor for the development of AF.

Indexed as

Atrial FibrillationTobacco Smoke PollutionWorkplaceAdultAir Pollution, IndoorChildCross-Sectional StudiesDemographyEnvironmental ExposureFemaleGlobal HealthHumansLongitudinal StudiesMalePregnancyPrenatal Exposure Delayed EffectsTobacco Smoke PollutionArrhythmiaAtrial fibrillationEpidemiologyLone atrial fibrillationPreventionRisk factorsSecondhand smoke

Identifiers

PMID26340844
PMCPMC4698178
OpenAlexW1814319499

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.