Evidence map›Paper›PMID 26340814›Full record

ArticleEuropean radiology2016

Coronary calcium screening with dual-source CT: reliability of ungated, high-pitch chest CT in comparison with dedicated calcium-scoring CT.

Antoine Hutt, Alain Duhamel, Valérie Deken, Jean-Baptiste Faivre, Francesco Molinari, Jacques Remy, Martine Remy-Jardin

Abstract read
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In one paragraph

Article in European radiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  13. Reporting Coronary Artery Calcium on Low-Dose Computed Tomography Impacts Statin Management in a Lung Cancer Screening Population.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2022
    Article
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  18. Coronary artery calcification in lung cancer screening.Translational lung cancer research · 2018
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Antoine HuttDepartment of Thoracic Imaging, Hospital Calmette (EA 2694), CHRU et Université de Lille, Lille, France.
Alain DuhamelDepartment of Biostatistics (EA 2694), CHRU et Université de Lille, Lille, France.
Valérie DekenDepartment of Biostatistics (EA 2694), CHRU et Université de Lille, Lille, France.
Jean-Baptiste FaivreDepartment of Thoracic Imaging, Hospital Calmette (EA 2694), CHRU et Université de Lille, Lille, France.
Francesco MolinariDepartment of Radiology, Centre Hospitalier Général de Tourcoing, Tourcoing, France.
Jacques RemyDepartment of Thoracic Imaging, Hospital Calmette (EA 2694), CHRU et Université de Lille, Lille, France.
Martine Remy-JardinDepartment of Thoracic Imaging, Hospital Calmette (EA 2694), CHRU et Université de Lille, Lille, France. martine.remy@chru-lille.fr.
Université de Lille · FRHôpital Albert Calmette · FRCentre Hospitalier de Tourcoing · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the reliability of ungated, high-pitch dual-source CT for coronary artery calcium (CAC) screening. MATERIALS AND

methodsOne hundred and eighty-five smokers underwent a dual-source CT examination with acquisition of two sets of images during the same session: (a) ungated, high-pitch and high-temporal resolution acquisition over the entire thorax (i.e., chest CT); (b) prospectively ECG-triggered acquisition over the cardiac cavities (i.e., cardiac CT).

resultsSensitivity and specificity of chest CT for detecting positive CAC scores were 96.4 % and 100 %, respectively. There was excellent inter-technique agreement for determining the quantitative CAC score (ICC = 0.986). The mean difference between the two techniques was 11.27, representing 1.81 % of the average of the two techniques. The inter-technique agreement for categorizing patients into the four ranks of severity was excellent (weighted kappa = 0.95; 95 % CI 0.93-0.98). The inter-technique differences for quantitative CAC scores did not correlate with BMI (r = 0.05, p = 0.575) or heart rate (r = -0.06, p = 0.95); 87.2 % of them were explained by differences at the level of the right coronary artery (RCA: 0.8718; LAD: 0.1008; LCx: 0.0139; LM: 0.0136).

conclusionUngated, high-pitch dual-source CT is a reliable imaging mode for CAC screening in the conditions of routine chest CT examinations. KEY POINTS: • CAC is an independent risk factor for major cardiac events. • ECG-gated techniques are the reference standard for calcium scoring. • Great interest is directed toward calcium scoring on non-gated chest CT examinations. • Reliable calcium scoring can be obtained with dual-source CT in a high-pitch mode.

Indexed as

AdultAgedAged, 80 and overCalcinosisCardiac-Gated Imaging TechniquesCoronary Artery DiseaseCoronary VesselsElectrocardiographyFemaleHeart RateHumansMaleMiddle AgedRadiation DosageReproducibility of ResultsRisk FactorsCalcium scoreDual-source CTHigh pitchUngated-CT

Identifiers

PMID26340814
OpenAlexW1230072559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.