ArticlePloS one2015
SpAHA1 and SpSOS1 Coordinate in Transgenic Yeast to Improve Salt Tolerance.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- Genome-wide analysis of ascorbate peroxidase and functional characterization of SpAPX249b and SpAPX285c for salt tolerance in Sesuvium portulacastrum L.Plant cell reports · 2025Article
- From swamp to field: how genes from mangroves and its associates can enhance crop salinity tolerance.Molecular biology reports · 2024Review
- Genome-wide characterization of the CPA gene family in potato and a preliminary functional analysis of its role in NaCl tolerance.BMC genomics · 2024Article
- The Roles of Calcineurin B-like Proteins in Plants under Salt Stress.International journal of molecular sciences · 2023Review
- Architecture and autoinhibitory mechanism of the plasma membrane NaNature communications · 2023Article
- Genome-wide characterization ofFrontiers in plant science · 2023Article
- Article
- Transcriptome analysis reveals molecular mechanisms underlying salt tolerance in halophyteFrontiers in plant science · 2022Article
- The Calcium Sensor Calcineurin B-Like Proteins -Calcineurin B-Like Interacting Protein Kinases Is Involved in Leaf Development and Stress Responses Related to Latex Flow inFrontiers in plant science · 2022Article
- Structure, Function, and Regulation of the Plasma Membrane NaFrontiers in plant science · 2022Review
- Article
- Genome-wide identification and expression analysis of aquaporin family in Canavalia rosea and their roles in the adaptation to saline-alkaline soils and drought stress.BMC plant biology · 2021Article
- Ectopic Expression ofInternational journal of molecular sciences · 2021Article
- The protein kinase complex CBL10-CIPK8-SOS1 functions in Arabidopsis to regulate salt tolerance.Journal of experimental botany · 2020Article
- Review
- Co-expression of SpSOS1 and SpAHA1 in transgenic Arabidopsis plants improves salinity tolerance.BMC plant biology · 2019Article
- Functional Identification of Salt-Stress-Related Genes Using the FOX Hunting System fromInternational journal of molecular sciences · 2018Article
- Over-expression of a plasma membrane HProtoplasma · 2018Article
- Molecular Cloning and Functional Characterization of the Dehydrin (Frontiers in plant science · 2018Article
- Expression Patterns and Identified Protein-Protein Interactions Suggest That Cassava CBL-CIPK Signal Networks Function in Responses to Abiotic Stresses.Frontiers in plant science · 2018Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plant cells, the plasma membrane Na+/H+ antiporter SOS1 (salt overly sensitive 1) mediates Na+ extrusion using the proton gradient generated by plasma membrane H+-ATPases, and these two proteins are key plant halotolerance factors. In the present study, two genes from Sesuvium portulacastrum, encoding plasma membrane Na+/H+ antiporter (SpSOS1) and H+-ATPase (SpAHA1), were cloned. Localization of each protein was studied in tobacco cells, and their functions were analyzed in yeast cells. Both SpSOS1 and SpAHA1 are plasma membrane-bound proteins. Real-time polymerase chain reaction (PCR) analyses showed that SpSOS1 and SpAHA1 were induced by salinity, and their expression patterns in roots under salinity were similar. Compared with untransformed yeast cells, SpSOS1 increased the salt tolerance of transgenic yeast by decreasing the Na+ content. The Na+/H+ exchange activity at plasma membrane vesicles was higher in SpSOS1-transgenic yeast than in the untransformed strain. No change was observed in the salt tolerance of yeast cells expressing SpAHA1 alone; however, in yeast transformed with both SpSOS1 and SpAHA1, SpAHA1 generated an increased proton gradient that stimulated the Na+/H+ exchange activity of SpSOS1. In this scenario, more Na+ ions were transported out of cells, and the yeast cells co-expressing SpSOS1 and SpAHA1 grew better than the cells transformed with only SpSOS1 or SpAHA1. These findings demonstrate that the plasma membrane Na+/H+ antiporter SpSOS1 and H+-ATPase SpAHA1 can function in coordination. These results provide a reference for developing more salt-tolerant crops via co-transformation with the plasma membrane Na+/H+ antiporter and H+-ATPase.
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