Evidence map›Paper›PMID 26340685›Full record

ArticleIEEE journal of biomedical and health informatics2015

Subject-Specific Sparse Dictionary Learning for Atlas-Based Brain MRI Segmentation.

Snehashis Roy, Qing He, Elizabeth Sweeney, Aaron Carass, Daniel S Reich, Jerry L Prince, Dzung L Pham

Open access · greenAbstract read
In one paragraph

Article in IEEE journal of biomedical and health informatics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 76 citations in OpenAlex.

  1. Article
  2. Article
  3. Unsupervised deep learning registration model for multimodal brain images.Journal of applied clinical medical physics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Snehashis Roy
Qing He
Elizabeth Sweeney
Aaron Carass
Daniel S Reich
Jerry L Prince
Dzung L Pham
Johns Hopkins University · USCenter for Neuroscience and Regenerative Medicine · USHenry M. Jackson Foundation · USNational Institute of Neurological Disorders and Stroke · US

Funding

Multimodal MRI in Multiple SclerosisZIANS003119 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI REICH, DANIEL · 2010 to 2025
$53.4M
Technological Assessment and Solutions Core - RC4P30AG021334 · NIA · JOHNS HOPKINS UNIVERSITY · PI Jeremy D Walston · 2003 to 2026
$33.2M
EPIDEMIOLOGY AND BIOSTATISTICS OF AGINGT32AG000247 · NIA · JOHNS HOPKINS UNIVERSITY · PI Karen J. Bandeen-Roche · 1996 to 2026
$13.2M
Statistical Methods for Multilevel Multivariate Functional StudiesR01NS060910 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Ciprian M Crainiceanu · 2009 to 2026
$8.3M
Statistical methods for large and complex databases of ultra-high-dimensionalR01NS085211 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SHINOHARA, RUSSELL TAKESHI · 2013 to 2017
$1.8M
Brain Image Analysis Tools for Quantitative Longitudinal Assessment of MSR01NS070906 · NINDS · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI PHAM, DZUNG L · 2010 to 2014
$1.7M
Multimodal image registration by proxy image synthesisR01EB017743 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2013 to 2015
$1.0M
MR Image Example-based Contrast Synthesis for Consistent Image AnalysisR21EB012765 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI PRINCE, JERRY L · 2011 to 2012
$430k
Intramural NIH HHSNIA NIH HHS P30 AG021334NIA NIH HHS T32 AG000247NIA NIH HHS T32AG021334NIBIB NIH HHS 1R01EB017743NIBIB NIH HHS R01 EB017743NIBIB NIH HHS R21 EB012765NIBIB NIH HHS R21EB012765NINDS NIH HHS R01 NS060910NINDS NIH HHS R01NS060910NINDS NIH HHS R01 NS070906NINDS NIH HHS R01NS070906NINDS NIH HHS R01 NS085211NINDS NIH HHS R01NS085211
6 · The paper itself

Abstract

Quantitative measurements from segmentations of human brain magnetic resonance (MR) images provide important biomarkers for normal aging and disease progression. In this paper, we propose a patch-based tissue classification method from MR images that uses a sparse dictionary learning approach and atlas priors. Training data for the method consists of an atlas MR image, prior information maps depicting where different tissues are expected to be located, and a hard segmentation. Unlike most atlas-based classification methods that require deformable registration of the atlas priors to the subject, only affine registration is required between the subject and training atlas. A subject-specific patch dictionary is created by learning relevant patches from the atlas. Then the subject patches are modeled as sparse combinations of learned atlas patches leading to tissue memberships at each voxel. The combination of prior information in an example-based framework enables us to distinguish tissues having similar intensities but different spatial locations. We demonstrate the efficacy of the approach on the application of whole-brain tissue segmentation in subjects with healthy anatomy and normal pressure hydrocephalus, as well as lesion segmentation in multiple sclerosis patients. For each application, quantitative comparisons are made against publicly available state-of-the art approaches.

Indexed as

Machine LearningAdultAgedAlgorithmsBrainFemaleHumansHydrocephalus, Normal PressureImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMultiple SclerosisYoung Adult

Identifiers

PMID26340685
PMCPMC4562064
OpenAlexW2163108348

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.