Evidence map›Paper›PMID 26339842›Full record

ArticlePlant signaling & behavior2015

A new temperature-insensitive allele of the Arabidopsis AXR6/CUL1 locus derived from a missense mutation in the C-terminal RBX1 binding region.

Yukiko Mori, Makoto Hayashi, Mikio Nishimura, Kotaro T Yamamoto

Abstract read
In one paragraph

Article in Plant signaling & behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Yukiko Moria Division of Biological Sciences; Graduate School of Environmental Earth Science; Hokkaido University ; Sapporo , Japan.
Makoto Hayashib Department of Bioscience ; Nagahama Institute of Bio-Science and Technology ; Nagahama , Japan.
Mikio Nishimurac National Institute for Basic Biology ; Okazaki , Japan.
Kotaro T Yamamotoa Division of Biological Sciences; Graduate School of Environmental Earth Science; Hokkaido University ; Sapporo , Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We isolated a new recessive allele at the AUXIN RESISTANT6/CULLIN1 (AXR6/CUL1) locus, axr6-101, from an EMS-mutagenized population of Arabidopsis thaliana, the Landsberg erecta ecotype. axr6-101 is auxin resistant and semi-dwarf similar to the other recessive axr6 mutants. The axr6-101 phenotype is caused by the E716K substitution of the CUL1 protein, which is likely to affect its ability to bind to the C-terminal RING domain of RING-box 1 (RBX1). The previously reported allele of AXR6, cul1-7, is caused by a substitution at T510 that binds to the N-terminal β-strand of RBX1. Although cul1-7 shows temperature-sensitive phenotype, the axr6-101 phenotype is largely unaffected by temperature. axr6-101 may provide an important genetic resource for study of the structure-function relationship of the CUL1 protein.

Indexed as

AllelesGenetic LociTemperatureArabidopsisArabidopsis ProteinsBinding SitesCarrier ProteinsCullin ProteinsIndoleacetic AcidsMutation, MissensePhenotypeProtein BindingArabidopsis ProteinsCarrier ProteinsCullin 1Cullin ProteinsIndoleacetic AcidsRBX1 protein, ArabidopsisArabidopsis thalianaauxin resistanceauxin signalingaxr6cullinmutant

Identifiers

PMID26339842
PMCPMC4883910

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.