ArticleNursing and midwifery studies2015
Effect of Melissa officinalis Capsule on the Intensity of Premenstrual Syndrome Symptoms in High School Girl Students.
Article in Nursing and midwifery studies, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 37 citations in OpenAlex.
- Effectiveness of Echium amoenum on premenstrual syndrome: a randomized, double-blind, controlled trial.BMC complementary medicine and therapies · 2020Trial
- Premenstrual syndrome: new insights into etiology and review of treatment methods.Frontiers in psychiatry · 2024Review
- A Systematic Review and Meta-Analysis of Premenstrual Syndrome with Special Emphasis on Herbal Medicine and Nutritional Supplements.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Role of Inflammation, Oxidative Stress, and Mitochondrial Changes in Premenstrual Psychosomatic Behavioral Symptoms with Anti-Inflammatory, Antioxidant Herbs, and Nutritional Supplements.Oxidative medicine and cellular longevity · 2022Article
- Using Medicinal Plants in Valmalenco (Italian Alps): From Tradition to Scientific Approaches.Molecules (Basel, Switzerland) · 2020Article
- The effect of Salvia officinalis extract on symptoms of flushing, night sweat, sleep disorders, and score of forgetfulness in postmenopausal women.Journal of family medicine and primary care · 2020Article
- The impact of education on attachment skills in the promotion of happiness among women with unplanned pregnancy.Journal of education and health promotion · 2020Article
- The effect of aromatherapy on mental, physical symptoms, and social functions of females with premenstrual syndrome: A randomized clinical trial.Journal of family medicine and primary care · 2019Article
- The Effects of Lemon balm on Menstrual Bleeding and the Systemic Manifestation of Dysmenorrhea.Iranian journal of pharmaceutical research : IJPR · 2018Article
- The Effect ofIranian journal of pharmaceutical research : IJPR · 2017Article
- Evaluation of the effect ofAvicenna journal of phytomedicineArticle
- The effectiveness and safety of Iranian herbal medicines for treatment of premenstrual syndrome: A systematic review.Avicenna journal of phytomedicineReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSeveral studies are conducted on Premenstrual Syndrome (PMS). However, a few herbal surveys exist on the treatment of PMS in Iran. Due to the sedative effects of Melissa officinalis (M. officinalis), this question comes to mind that "can it be used in the treatment of PMS symptoms?"
objectivesThe current study aimed to assess the effect of M. officinalis capsule on the intensity of PMS in high-school girls. MATERIALS AND
methodsA double-blind randomized, placebo-controlled trial was performed on 100 high school girls from 2013 to 2014. The intervention group (n = 50) received 1200 mg of M. officinalis essence daily from the first to the last day of their menstrual cycle for three consecutive cycles. The second group (n = 50) received the placebo. The premenstrual symptoms screening tool was used to assess the intensity of PMS symptoms in the two groups before and one, two, and three months after the intervention. The data were analyzed using paired t-test and repeated measures analysis of variance.
resultsThe results of repeated measures test revealed a significant reduction (P < 0.001) in PMS symptoms. Overall, the mean score of PMS intensity in the intervention group was 42.56 + 15.73 before the intervention and changed to 32.72 ± 13.24, 30.02 ± 12.08, and 13.90 ± 10.22 at the three consecutive months after the intervention, respectively (P = 0.001).
conclusionsM. officinalis capsules were effective in reduction of the PMS symptoms. Yet, application of this medication requires further investigations.
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