Evidence map›Paper›PMID 26339624›Full record

ReviewBioMed research international2015

Environmental Epigenetics: Crossroad between Public Health, Lifestyle, and Cancer Prevention.

Massimo Romani, Maria Pia Pistillo, Barbara Banelli

Abstract readReview
In one paragraph

Review in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Association of lncRNAJournal of genetics · 2021
    Pooled it
  2. Trial
  3. Predictive markers of endometriosis: a future perspective.Archives of gynecology and obstetrics · 2026
    Review
  4. Article
  5. Epitranscriptomic alterations induced by environmental toxins: implications for RNA modifications and disease.Genes and environment : the official journal of the Japanese Environmental Mutagen Society · 2025
    Review
  6. Review
  7. Epigenetic Modifications and Therapy in Uveitis.Frontiers in cell and developmental biology · 2021
    Review
  8. Review
  9. Review
  10. Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity.International journal of molecular sciences · 2020
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. The role of epigenetics in renal ageing.Nature reviews. Nephrology · 2017
    Review
  17. Review
  18. Review
  19. Observational
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Massimo RomaniLaboratory of Tumor Epigenetics, IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Maria Pia PistilloLaboratory of Tumor Epigenetics, IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, 16132 Genova, Italy.
Barbara BanelliLaboratory of Tumor Epigenetics, IRCCS AOU San Martino-IST, Largo Rosanna Benzi 10, 16132 Genova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epigenetics provides the key to transform the genetic information into phenotype and because of its reversibility it is considered an ideal target for therapeutic interventions. This paper reviews the basic mechanisms of epigenetic control: DNA methylation, histone modifications, chromatin remodeling, and ncRNA expression and their role in disease development. We describe also the influence of the environment, lifestyle, nutritional habits, and the psychological influence on epigenetic marks and how these factors are related to cancer and other diseases development. Finally we discuss the potential use of natural epigenetic modifiers in the chemoprevention of cancer to link together public health, environment, and lifestyle.

Indexed as

EnvironmentEpigenomicsChromatinDNA MethylationHistonesHumansLife StyleNeoplasmsPhenotypePublic HealthChromatinHistones

Identifiers

PMID26339624
PMCPMC4538403

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.