Evidence map›Paper›PMID 26339602›Full record

ArticleBioMed research international2015

Gestational Hypertension and Organophosphorus Pesticide Exposure: A Cross-Sectional Study.

Caterina Ledda, Maria Fiore, Lory Santarelli, Massimo Bracci, Giuseppe Mascali, Maria Grazia D'Agati, Alfredo Busà, Margherita Ferrante, Venerando Rapisarda

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Occupational Risk Factors and Hypertensive Disorders in Pregnancy: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modifiable contributing factors to COVID-19: A comprehensive review.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Review
  9. Article
  10. Article
  11. Oxidative stress and DNA damage in agricultural workers after exposure to pesticides.Journal of occupational medicine and toxicology (London, England) · 2021
    Article
  12. Article
  13. Endocrine Disruptors in Water and Their Effects on the Reproductive System.International journal of molecular sciences · 2020
    Review
  14. Review
  15. Article
  16. Home proximity to flower plantations and higher systolic blood pressure among children.International journal of hygiene and environmental health · 2018
    Article
  17. Article
  18. Mutagenic and DNA repair activity in traffic policemen: a case-crossover study.Journal of occupational medicine and toxicology (London, England) · 2018
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Caterina LeddaHygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.
Maria FioreHygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.
Lory SantarelliOccupational Medicine, Department of Clinical and Molecular Science, Polytechnic University of Marche, Via Tronto 10/A, 60100 Ancona, Italy.
Massimo BracciOccupational Medicine, Department of Clinical and Molecular Science, Polytechnic University of Marche, Via Tronto 10/A, 60100 Ancona, Italy.
Giuseppe MascaliDivision of Clinical Pathology, Hospital of Taormina, ASP Messina, C/da Sirina, 98039 Taormina, Italy.
Maria Grazia D'AgatiHygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.
Alfredo BusàDivision of Cardiology, Hospital of Lentini, ASP Siracusa, C/da Colle Roggio, 96016 Lentini, Italy.
Margherita FerranteHygiene and Public Health, Department of G.F. Ingrassia, University of Catania, Via Santa Sofia 87, 95123 Catania, Italy.
Venerando RapisardaOccupational Medicine, "Policlinico-Vittorio Emanuele" University Hospital, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.
University of Catania · ITMarche Polytechnic University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertension is the most common medical problem encountered during pregnancy, complicating 2-3% of pregnancies. High blood pressure (BP) with diastolic BP ≥ 90 mm Hg and/or systolic BP ≥ 140 mm Hg arising after week 22 of pregnancy and resolving after delivery is defined as gestational hypertension (GHY). The aim of this cross-sectional study was to investigate whether occupational and/or environmental exposure to organophosphorus (OP) pesticide affects GHY. Women at approximately 22 weeks of gestation were recruited. OP pesticide exposure in the first trimester of pregnancy was classified into four categories: no exposure, indirect exposure, domestic exposure, and occupational exposure. Application of the exclusion criteria left 2203 participants (mean age 30.4 ± 11.6 years). Data analysis showed that in women with indirect OP pesticide exposure the incidence of GHY was slightly higher than that in the world population, whereas domestic exposure involved a 7% increase and occupational exposure a 12% increase. Analysis of the pesticides used by participants highlighted a possible role for malathion and diazinon (adjusted OR 1.09 and 1.14, resp.). Further investigation of exposed workers and the general population is clearly warranted given the broad diffusion of OP pesticides and their possible public health impact, maybe by including a wider range of health outcomes.

Indexed as

Environmental ExposureOccupational ExposureAdultBlood PressureCross-Sectional StudiesFemaleHumansHypertension, Pregnancy-InducedOrganophosphorus CompoundsPesticidesPregnancyOrganophosphorus CompoundsPesticides

Identifiers

PMID26339602
PMCPMC4538315
OpenAlexW1562348550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.