Evidence map›Paper›PMID 26339534›Full record

ReviewAdvances in wound care2015

Challenges in the Treatment of Chronic Wounds.

Robert G Frykberg, Jaminelli Banks

5 registry-linked trialsAbstract readReview
In one paragraph

Review in Advances in wound care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 962 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
962citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03198169 naterminatednot on this mapstarted 2017, after this paper: background citation

2-part, Randomized, Double Blind, Prospective, Single Center, Controlled Trial to Investigate an Antimicrobial Skin and Wound Cleanser and an Antimicrobial Barrier Film Dressing on the Rates of Healing for Chronic Wounds

TypeinterventionalSponsorAtteris Healthcare, LLCRan2017 to 2017Enrolled4ConditionsChronic WoundsArmsAtteris Antimicrobial Skin and Wound Cleanser, Atteris Antimicrobial Barrier Film Dressing
NCT03369756 naterminatednot on this mapstarted 2018, after this paper: background citation

A Prospective Study of Quality of Life in Patients With Chronic Leg Wound(s) Treated With Prontosan® Wound Irrigation Solution and Prontosan® Wound Gel

TypeinterventionalSponsorB. Braun Medical Inc.Ran2018 to 2019Enrolled43ConditionsWound of Lower Leg (Physical Finding)ArmsProntosan Wound Irrigation Solution and Prontosan Wound Gel
NCT03526913 nacompletednot on this mapstarted 2016, after this paper: background citation

Role of Platelet Rich Plasma in Enhancing Graft Take in Chronic Venous Ulcers

TypeinterventionalSponsorNoha Mohsen OmarRan2016 to 2018Enrolled20ConditionsChronic Venous Hypertension With Ulcer and Inflammation, Chronic Ulcer of Leg or FootArmsPRP, STSG
NCT04746573 completednot on this mapstarted 2021, after this paper: background citation

A Single Center Pilot Study to Examine the Effect of NATROX Oxygen Wound Therapy on Non-healing Wounds and the Practical Implication of Introducing a Remote Monitoring and Telehealth Solution to Manage These Complex Patients in the Home Setting.

TypeobservationalSponsorInotec AMD LimitedRan2021 to 2022Enrolled8ConditionsNon-healing WoundsArmsNatrox Topical Oxygen Therapy
NCT05883098 nacompletednot on this mapstarted 2022, after this paper: background citation

Effectiveness of Supra SDRM® vs. Fibracol Plus Collagen in the Treatment of Diabetic Foot Ulcers: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorPolymedics Innovations Inc.Ran2022 to 2023Enrolled30ConditionsDiabetic Foot, Ulcer Foot, Wound HealArmsWound debridement, Wound closure matrix application
3 · Its place in the literature

Who cites it

962 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  6. The Effect ofNutrients · 2025
    Pooled it
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  10. Review
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  18. Advancements in Functional Polymeric Scaffolds for Scar-Free Skin Regeneration.Polymer science & technology (Washington, D.C.) · 2026
    Review
  19. Article
  20. Article

902 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert G FrykbergPhoenix VA Health Care System , Phoenix, Arizona.
Jaminelli BanksPhoenix VA Health Care System , Phoenix, Arizona.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID26339534
PMCPMC4528992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.