ArticleOpen heart
Gender differences in health-related quality of life in patients undergoing coronary angiography.
Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02304744 (Utrecht Coronary Biobank), which is not on this map. Cited by 28 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Utrecht Coronary Biobank (UCORBIO)
Who cites it
28 citing papers in PubMed.
- Sex, body mass index, and blood pressure are related to aortic characteristics in healthy, young adults using magnetic resonance vessel wall imaging: the AMBITYON study.Magma (New York, N.Y.) · 2018Trial
- Sex differences in health-related quality of life among adults in the US: results from the medical expenditures panel survey data.BMC public health · 2025Article
- Health-related quality of life predicts prognosis in individuals with COPD hospitalized with community-acquired pneumonia - a prospective cohort study.Scientific reports · 2024Article
- Article
- Randomized Comparison of the Outcome of Single Versus Multiple Arterial Grafts trial (ROMA):Women-a trial dedicated to women to improve coronary bypass outcomes.The Journal of thoracic and cardiovascular surgery · 2024Article
- Sex and Gender Differences in Psychosocial Risk Profiles Among Patients with Coronary Heart Disease - the THORESCI-Gender Study.International journal of behavioral medicine · 2024Article
- Technical Report: A Comprehensive Comparison between Different Quantification Versions of Nightingale Health'sMetabolites · 2023Article
- Health-related quality of life in a european sample of adults with early-treated classical PKU.Orphanet journal of rare diseases · 2023Article
- Health-Related Quality of Life after Cataract Surgery in Armenia: A Cross-Sectional Survey.Healthcare (Basel, Switzerland) · 2023Article
- Clinical and psychological characteristics of patients with ischemia and non-obstructive coronary arteries (INOCA) and obstructive coronary artery disease.American heart journal plus : cardiology research and practice · 2023Article
- Sex differences in quality of life of patients following percutaneous coronary intervention in Vietnam.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- Health-Related Quality of Life (HRQoL) and the Effect on Outcome in Patients Presenting with Coronary Artery Disease and Treated with Percutaneous Coronary Intervention (PCI): Differences Noted by Sex and Age.Journal of clinical medicine · 2022Article
- Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: Quality of Life (ROMA:QOL) - Rationale and Study Protocol.European heart journal. Quality of care & clinical outcomes · 2022Article
- Quality of life in liver transplant recipients during the Corona virus disease 19 pandemic: A multicentre study.Liver international : official journal of the International Association for the Study of the Liver · 2022Article
- Measurement invariance of the Seattle Angina Questionnaire in coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- How gender-specific are predictors of post-MI HRQoL? A longitudinal study.Health and quality of life outcomes · 2020Article
- Using path analysis to investigate the relationships between depression, anxiety, and health-related quality of life among patients with coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019Article
- Validation of Chichewa Short Musculoskeletal Function Assessment (SMFA) questionnaire: A cross-sectional study.Malawi medical journal : the journal of Medical Association of Malawi · 2019Article
- Health related quality of life in sepsis survivors from the Prehospital Antibiotics Against Sepsis (PHANTASi) trial.PloS one · 2019Article
- Gender Differences in Patient-Reported Outcomes Among Adults With Atherosclerotic Cardiovascular Disease.Journal of the American Heart Association · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth-related quality of life (HRQOL) reflects the general well-being of individuals. In patients with coronary artery disease (CAD), HRQOL is compromised. Female patients with CAD have been reported to have lower HRQOL. In this study, we investigate gender differences in HRQOL and in associations of patient characteristics with HRQOL in patients with coronary angiography (CAG).
methodsWe cross-sectionally analysed patients from the Utrecht Coronary Biobank undergoing CAG. All patients filled in an HRQOL questionnaire (RAND-36 and EuroQoL) on inclusion. RAND-36 and EuroQoL HRQOL measures were compared between the genders across indications for CAG, CAD severity and treatment of CAD. RAND-36 HRQOL measures were compared with the general Dutch population. Additionally, we assessed interactions of gender with patient characteristics in their association with HRQOL (EuroQoL).
resultsWe included 1421 patients (1020 men and 401 women) with a mean age of 65 in our analysis. Women reported lower HRQOL measures than men (mean EuroQoL self-rated health grade 6.84±1.49 in men, 6.46±1.40 in women, p<0.001). The reduction in RAND-36 HRQOL as compared with the general Dutch population was larger in women than in men. From regression analysis, we found that diabetes, a history of cardiovascular disease and symptoms of shortness of breath determined HRQOL (EuroQoL) more strongly in men than in women.
conclusionsWomen reported lower HRQOL than men throughout all indications for CAG and regardless of CAD severity or treatment. As compared with the general population, the reduction in HRQOL was more extreme in women than in men. Evident gender differences were found in determinants of HRQOL in patients undergoing CAG, which deserve attention in future research.
trial registrationNCT02304744 (clinicaltrials.gov).
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