ArticleInternational journal of clinical and experimental pathology2015
Epstein-Barr virus associated T-cell lymphoproliferative disease misdiagnosed as ulcerative colitis: a case report.
Article in International journal of clinical and experimental pathology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Clinical characteristics and literature review of chronic active Epstein-Barr virus-associated enteritis.Clinical case reports · 2024Article
- Rare case of EBV-induced colitis in an immunocompetent individual.BMJ open gastroenterology · 2020Article
- Chronic Active Epstein-Barr Virus-Associated Enteritis: CT Findings and Clinical Manifestation.BioMed research international · 2020Article
- Intestinal ulcers as an initial finding in EBV-associated lymphoproliferative disorder: A case report.Medicine · 2020Article
- A new therapy in Epstein-Barr virus-associated lymphoproliferative disease: a case report and a revision of the literature.Italian journal of pediatrics · 2019Review
- Necrotizing pancreatitis after removal of prophylactically placed pancreatic stent.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- EBV-associated lymphoproliferative disorder involving the gastrointestinal tract which mimic IBD in immunocompetent patients: case reports and literature review.International journal of colorectal disease · 2019Review
- Epstein-Barr virus-associated lymphoproliferative disorder in colon with the development of hemophagocytic syndrome of an immunocompetent patient.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- Necrotizing pancreatitis after removal of prophylactically placed pancreatic stent.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019Article
- Epstein-Barr virus (EBV) status in colorectal cancer: a mini review.Human vaccines & immunotherapeutics · 2019Review
- Epstein-Barr Virus-Associated T-Cell Lymphoproliferative Disorder Presenting as Chronic Diarrhea and Intestinal Bleeding: A Case Report.Frontiers in immunology · 2018Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epstein-Barr virus (EBV)-associated T-cell lymphoproliferative disease (LPD) is not uncommon in China, but gastrointestinal involvement is very rare. We report on an immunocompetent patient with EBV-associated T-cell LPD of the colon. The 26-year-old man was initially misdiagnosed with ulcerative colitis (UC). A colon biopsy revealed the presence of small to medium-sized lymphoid cells infiltrating the intestinal wall. The neoplastic cells expressed CD3, CD5, and granzyme B, not CD56. EBV-encoded small ribonucleic acid was detected in the tumor cells of the colon as well as the lymph node, and the T-cell receptor gene rearrangement result displayed δ gene monoclonal rearrangement. The patient died 2 moths after the diagnosis. The clinical course of EBV-associated T-cell LPD is aggressive and the prognosis is poor, the wrong diagnosis may delay treatment. Therefore, we should be very careful to prevent misdiagnosis. When patients have multiple intestinal ulcers that are not typical of UC and the clinical course is unusual, although morphology looks like inflammatory change, pathologist should consider the possibility of EBV-associated LPD. The treatment strategy and prognosis of these two diseases are different.
Indexed as
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26339440PMC4555768W1230812464What OpenQuestion holds
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