ArticleBiomicrofluidics2015
Convenient surface functionalization of whole-Teflon chips with polydopamine coating.
Article in Biomicrofluidics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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Who cites it
4 citing papers in PubMed.
- Effect of Fluorophilic- and Hydrophobic-Modified Polyglycerol-Based Coatings on the Wettability of Low Surface Energy Polymers.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- Challenge of material haemocompatibility for microfluidic blood-contacting applications.Frontiers in bioengineering and biotechnology · 2023Review
- Highly hydrophobic polytetrafluoroethylene particle immobilization via polydopamine anchor layer on nitric oxide releasing polymer for biomedical applications.Journal of colloid and interface science · 2021Article
- Patterning Perfluorinated Surface with Graphene Oxide and the Microarray Applications.Micromachines · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents a convenient strategy to modify the surface of whole-Teflon microfluidic chips by coating the channel walls with a thin layer of polydopamine (PDA) film, which is formed by oxidation-induced self-polymerization of dopamine in alkaline solution. Two coating strategies, static incubation and dynamic flow, are demonstrated and used for tuning the physical and chemical properties of the coated channel walls. The functionalized surfaces were investigated with the contact angle, X-ray photoelectron spectroscopy, and atomic force microscopy measurements. The coating time was optimized according to the fluorescent intensity of the green fluorescent protein immobilized on the modified surface. Applications of the PDA-modified Teflon microchips in bioanalysis were demonstrated with a typical sandwich immunoassay. Moreover, long-term cell culture experiments on modified and native Teflon chips revealed that the chip biocompatibility can be greatly improved with PDA coating. The results indicate that the surface properties of the Teflon can be easily controlled by the PDA modification, thus greatly expanding the application scope of whole-Teflon chips for various chemical and biological research fields.
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Registered trials
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