Evidence map›Paper›PMID 26339206›Full record

ReviewThe Yale journal of biology and medicine2015

Reducing Fatal Opioid Overdose: Prevention, Treatment and Harm Reduction Strategies.

Kathryn F Hawk, Federico E Vaca, Gail D'Onofrio

Abstract readReview
In one paragraph

Review in The Yale journal of biology and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

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  8. Navigating Substance Use Care in the Emergency Department: A Scoping Review.Journal of the American College of Emergency Physicians open · 2026
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kathryn F HawkDepartment of Emergency Medicine, Yale University, New Haven, Connecticut.
Federico E VacaDepartment of Emergency Medicine, Yale University, New Haven, Connecticut.
Gail D'OnofrioDepartment of Emergency Medicine, Yale University, New Haven, Connecticut.

Funding

Yale Drug use, Addiction and HIV Research Scholars (DAHRS)K12DA033312 · NIDA · YALE UNIVERSITY · PI Gail D'Onofrio, Patrick O'Connor · 2013 to 2026
$7.2M
NIDA NIH HHS 5K12DA033312-02
6 · The paper itself

Abstract

The opioid overdose epidemic is a major threat to the public's health, resulting in the development and implementation of a variety of strategies to reduce fatal overdose. Many strategies are focused on primary prevention and increased access to effective treatment, although the past decade has seen an exponential increase in harm reduction initiatives. To maximize identification of opportunities for intervention, initiatives focusing on prevention, access to effective treatment, and harm reduction are examined independently, although considerable overlap exists. Particular attention is given to harm reduction approaches, as increased public and political will have facilitated widespread implementation of several initiatives, including increased distribution of naloxone and policy changes designed to increase bystander assistance during a witnessed overdose.

Indexed as

Harm ReductionDrug OverdoseEvidence-Based MedicineHumansIncidenceNaloxoneNarcotic AntagonistsOpioid-Related DisordersRisk FactorsTreatment OutcomeNaloxoneNarcotic Antagonistsharm reductionnaloxoneopioid overdoseoverdoseprescription drug abuse

Identifiers

PMID26339206
PMCPMC4553643

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.