Evidence map›Paper›PMID 26339204›Full record

Trial reportThe Yale journal of biology and medicine2015

A Feasibility Study of Bilateral Anodal Stimulation of the Prefrontal Cortex Using High-Definition Electrodes in Healthy Participants.

Jiansong Xu, Stephen M Healy, Dennis Q Truong, Abhishek Datta, Marom Bikson, Marc N Potenza

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in The Yale journal of biology and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Adverse events of tDCS and tACS: A review.Clinical neurophysiology practice · 2017
    Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jiansong XuDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut.
Stephen M HealyDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut.
Dennis Q TruongDepartment of Biomedical Engineering, City University of New York, City College, New York, New York.
Abhishek DattaDepartment of Biomedical Engineering, City University of New York, City College, New York, New York.
Marom BiksonDepartment of Biomedical Engineering, City University of New York, City College, New York, New York.
Marc N PotenzaDepartment of Psychiatry, Yale School of Medicine, New Haven, Connecticut ; Child Study Center, Yale School of Medicine, New Haven, Connecticut ; Department of Neurobiology, Yale School of Medicine, New Haven, Connecticut.
Yale University · US

Funding

Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2010 to 2013
$3.6M
FMRI & DTI Study on Neural Predictor of Treatment Outcome of Cocaine DependenceK01DA027750 · NIDA · YALE UNIVERSITY · PI XU, JIANSONG · 2010 to 2014
$881k
NIDA NIH HHS K01 DA027750NIDA NIH HHS K01DA027750NIDA NIH HHS P20 DA027844
6 · The paper itself

Abstract

Transcranial direct current stimulation (tDCS) studies often use one anode to increase cortical excitability in one hemisphere. However, mental processes may involve cortical regions in both hemispheres. This study's aim was to assess the safety and possible effects on affect and working memory of tDCS using two anodes for bifrontal stimulation. A group of healthy subjects participated in two bifrontal tDCS sessions on two different days, one for real and the other for sham stimulation. They performed a working memory task and reported their affect immediately before and after each tDCS session. Relative to sham, real bifrontal stimulation did not induce significant adverse effects, reduced decrement in vigor-activity during the study session, and did not improve working memory. These preliminary findings suggest that bifrontal anodal stimulation is feasible and safe and may reduce task-related fatigue in healthy participants. Its effects on neuropsychiatric patients deserve further study.

Indexed as

ElectrodesAdolescentAdultAffectCognitionFeasibility StudiesFemaleHumansMaleMemory, Short-TermMental DisordersMiddle AgedPrefrontal CortexTranscranial Direct Current StimulationYoung Adultaffectcognitive functionnon-invasive brain stimulationtDCSworking memory

Identifiers

PMID26339204
PMCPMC4553641
OpenAlexW2410535206

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.