ArticleBioinformation2015
PHYSICO2: an UNIX based standalone procedure for computation of physicochemical, window-dependent and substitution based evolutionary properties of protein sequences along with automated block preparation tool, version 2.
Article in Bioinformation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Intrinsic basis of thermostability of prolyl oligopeptidase from Pyrococcus furiosus.Scientific reports · 2021Article
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- Salt-bridges in the microenvironment of stable protein structures.Bioinformation · 2020Article
- Structural insights from water-ferredoxin interaction in mesophilic algae and halophilic archaea.Bioinformation · 2019Article
- Insights from the salt bridge analysis of malate dehydrogenase from H. salinarum and E.coli.Bioinformation · 2019Article
- Analysis of salt-bridges in prolyl oligopeptidase from Pyrococcus furiosus and Homo sapiens.Bioinformation · 2019Article
- AUTOMINv1.0: an automation for minimization of Protein Data Bank files and its usage.Bioinformation · 2018Article
- PROPAB: Computation of Propensities and Other Properties from Segments of 3D structure of Proteins.Bioinformation · 2018Article
- POWAINDv1.0: A Program for Protein-Water Interactions Determination.Bioinformation · 2018Article
- Insight into SNPs and epitopes of E protein of newly emerged genotype-I isolates of JEV from Midnapur, West Bengal, India.BMC immunology · 2017Article
- Substitutional Analysis of Orthologous Protein Families Using BLOCKS.Bioinformation · 2017Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAutomated genome sequencing procedure is enriching the sequence database very fast. To achieve a balance between the entry of sequences in the database and their analyses, efficient software is required. In this end PHYSICO2, compare to earlier PHYSICO and other public domain tools, is most efficient in that it i] extracts physicochemical, window-dependent and homologousposition-based-substitution (PWS) properties including positional and BLOCK-specific diversity and conservation, ii] provides users with optional-flexibility in setting relevant input-parameters, iii] helps users to prepare BLOCK-FASTA-file by the use of Automated Block Preparation Tool of the program, iv] performs fast, accurate and user-friendly analyses and v] redirects itemized outputs in excel format along with detailed methodology. The program package contains documentation describing application of methods. Overall the program acts as efficient PWS-analyzer and finds application in sequence-bioinformatics. AVAILABILITY: PHYSICO2: is freely available at http://sourceforge.net/projects/physico2/ along with its documentation at https://sourceforge.net/projects/physico2/files/Documentation.pdf/download for all users.
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