ArticleEuropean journal of applied physiology2015
Dietary nitrate reduces the O2 cost of desert marching but elevates the rise in core temperature.
Article in European journal of applied physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- A systematic review: Role of dietary supplements on markers of exercise-associated gut damage and permeability.PloS one · 2022Pooled it
- Dietary berberine supplementation improves select physiological and psychological responses during exertional heat stress: A pilot study in young adults.Physiological reports · 2026Trial
- Acute Beetroot Juice Supplementation Attenuates Morning-Associated Decrements in Supramaximal Exercise Performance in Trained Sprinters.International journal of environmental research and public health · 2021Trial
- Dietary curcumin supplementation does not alter peripheral blood mononuclear cell responses to exertional heat stress.European journal of applied physiology · 2018Trial
- Influence of dietary nitrate supplementation on local sweating and cutaneous vascular responses during exercise in a hot environment.European journal of applied physiology · 2018Trial
- Acute L-arginine supplementation has no effect on cardiovascular or thermoregulatory responses to rest, exercise, and recovery in the heat.European journal of applied physiology · 2016Trial
- Review
- Exertional heat stroke: nutritional considerations.Experimental physiology · 2022Review
- Dietary nitrate supplementation does not influence thermoregulatory or cardiovascular strain in older individuals during severe ambient heat stress.Experimental physiology · 2020Article
- The Gastrointestinal Exertional Heat Stroke Paradigm: Pathophysiology, Assessment, Severity, Aetiology and Nutritional Countermeasures.Nutrients · 2020Review
- Supplementary Nitric Oxide Donors and Exercise as Potential Means to Improve Vascular Health in People with Type 1 Diabetes: Yes to NO?Nutrients · 2019Review
- An acute dose of inorganic dietary nitrate does not improve high-intensity, intermittent exercise performance in temperate or hot and humid conditions.European journal of applied physiology · 2019Article
- Effect of dietary nitrate supplementation on thermoregulatory and cardiovascular responses to submaximal cycling in the heat.European journal of applied physiology · 2018Article
- "Beet-ing" the Mountain: A Review of the Physiological and Performance Effects of Dietary Nitrate Supplementation at Simulated and Terrestrial Altitude.Sports medicine (Auckland, N.Z.) · 2017Review
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDietary nitrate (NO3 (-)) supplementation reduces the O2 cost of fixed-workload tasks performed in temperate environments but has not been examined in the heat. If this effect were retained it could reduce heatstroke risk in military personnel that are deployed for desert combat.
methodsNine men completed three 45 min loaded battle marches at a standard cadence (4.83 km h(-1)/1.5 % grade) while wearing full combat gear [BDU, boots, body armor (8 kg), NBC suit] and carrying a loaded rucksack (16 kg). The 1st March (FAM) commenced in a temperate environment. The 2nd and 3rd commenced in simulated dry desert conditions (41 °C/20 % RH) and required subjects to ingest the beetroot juice equivalent of 8.4 mmol NO3 (-) (BRJ) or a NO3 (-) depleted placebo (PLA) for 6 days prior. VO2, VCO2, V E, core (T re), skin (T sk), and mean body (T b) temperatures, HR, and physiological strain index (PSI) were measured continuously. Thermal sensation, generalized discomfort, and perceived exertion (RPE) were measured at 5 min intervals. Heat storage (HS) was calculated. Blood markers of gastrointestinal permeability (TNF, Il-6, HO-1) were measured before and after exercise.
resultsVO2 in BRJ was lower than PLA from 1 to 12; 16 to 26; and 29 to 45 min of exercise (p < 0.05). VCO2 in BRJ was lower than PLA from 1 to 12 min (p < 0.05). V E in BRJ was lower than PLA from 1 to 20 min of exercise (p < 0.05). T re and T b in BRJ exceeded PLA from 16 to 45 min (p < 0.05). TNF, Il-6, and HO-1 were reduced in BRJ (p < 0.05) while HR, PSI, Tsk, and HS were not altered (p > 0.05). Thermal sensation, generalized discomfort, and RPE were elevated in BRJ from 40 to 45, 25 to 45, and 10 to 45 min, respectively (p < 0.01).
conclusionMetabolic efficiency was improved in BRJ. Paradoxically, body temperatures rose more. This was not due to gut permeability. Therefore, we speculate that based on elimination of other possibilities, blood redistribution from skin to skeletal muscle may have contributed to impaired heat exchange.
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