Evidence map›Paper›PMID 26338783›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2016

Quality of HIV Care and Mortality Rates in HIV-Infected Patients.

Philip Todd Korthuis, Kathleen A McGinnis, Kevin L Kraemer, Adam J Gordon, Melissa Skanderson, Amy C Justice, Stephen Crystal, Matthew Bidwell Goetz, Cynthia L Gibert, David Rimland and 10 more

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Philip Todd KorthuisOregon Health & Science University, Portland.
Kathleen A McGinnisVA Pittsburgh Healthcare System.
Kevin L KraemerVA Pittsburgh Healthcare System.
Adam J GordonCenter for Health Equity Research and Promotion.
Melissa SkandersonVA Pittsburgh Healthcare System.
Amy C JusticeDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine.
Stephen CrystalThe Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, New Jersey.
Matthew Bidwell GoetzVA Greater Los Angeles Healthcare System and David Geffen School of Medicine at UCLA.
Cynthia L GibertVA Medical Center and George Washington University Medical Center, Washington D.C.
David RimlandVA Medical Center and Emory University School of Medicine, Atlanta, Georgia.
Lynn E FiellinDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine.
Julie R GaitherDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven.
Karen WangDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine.
Steven M AschVA Greater Palo Alto Healthcare System and Stanford University, California.
Donald Keith McInnesBoston University, Massachusetts.
Michael E OhlUniversity of Iowa Carver College of Medicine, Iowa City.
Kendall BryantHIV/AIDS Research, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland.
Janet P TateDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine.
Mona DuggalVA Connecticut Care System, West Haven, Connecticut.
David A FiellinDivision of General Internal Medicine and the Center for Interdisciplinary Research on AIDS, Yale University School of Medicine.

Funding

Alcohol and Multisubstance Use in the Veterans Aging Cohort StudyU01AA020790 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$7.7M
Sex Disparities in Overall Response to ART Among HIV Infected IndividualsU24AA020794 · NIAAA · YALE UNIVERSITY · PI JUSTICE, AMY CAROLINE · 2011 to 2020
$5.5M
Translational Research on Alcohol, Immunodeficiency, and Aging In COMpAAASU24AA022001 · NIAAA · YALE UNIVERSITY · PI BRANDT, CYNTHIA A. · 2012 to 2020
$3.2M
Comparative Effectiveness of Alcohol and Drug Treatment in HIV-Infected VeteransR01AA022886 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI KRAEMER, KEVIN L · 2014 to 2018
$2.4M
Quality Outcomes for Patients with Drug Abuse and HIVK23DA019809 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD · 2007 to 2011
$892k
NIAAA NIH HHS R01 AA022886NIAAA NIH HHS R01-AA022886NIAAA NIH HHS U01 AA020790NIAAA NIH HHS U01-AA020790NIAAA NIH HHS U24 AA020794NIAAA NIH HHS U24-AA020794NIAAA NIH HHS U24 AA022001NIDA NIH HHS K23 DA019809
6 · The paper itself

Abstract

backgroundThe Patient Protection and Affordable Care Act encourages healthcare systems to track quality-of-care measures; little is known about their impact on mortality rates. The objective of this study was to assess associations between HIV quality of care and mortality rates.

methodsA longitudinal survival analysis of the Veterans Aging Cohort Study included 3038 human immunodeficiency virus (HIV)-infected patients enrolled between June 2002 and July 2008. The independent variable was receipt of ≥80% of 9 HIV quality indicators (QIs) abstracted from medical records in the 12 months after enrollment. Overall mortality rates through 2014 were assessed from the Veterans Health Administration, Medicare, and Social Security National Death Index records. We assessed associations between receiving ≥80% of HIV QIs and mortality rates using Kaplan-Meier survival analysis and adjusted Cox proportional hazards models. Results were stratified by unhealthy alcohol and illicit drug use.

resultsThe majority of participants were male (97.5%) and black (66.8%), with a mean (standard deviation) age of 49.0 (8.8) years. Overall, 25.9% reported past-year unhealthy alcohol use and 28.4% reported past-year illicit drug use. During 24 805 person-years of follow-up (mean [standard deviation], 8.2 [3.3] years), those who received ≥80% of QIs experienced lower age-adjusted mortality rates (adjusted hazard ratio, 0.75; 95% confidence interval, .65-.86). Adjustment for disease severity attenuated the association.

conclusionsReceipt of ≥80% of select HIV QIs is associated with improved survival in a sample of predominantly male, black, HIV-infected patients but was insufficient to overcome adjustment for disease severity. Interventions to ensure high-quality care and address underlying chronic illness may improve survival in HIV-infected patients.

Indexed as

Quality of Health CareFemaleHIV InfectionsHumansLongitudinal StudiesMaleMiddle AgedMortalitySurvival AnalysisVeteransalcoholhealth careHIVopioid-related disordersquality of health care

Identifiers

PMID26338783
PMCPMC4690479

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.