ArticleThe Veterinary record2015
Specificity of the comparative skin test for bovine tuberculosis in Great Britain.
Article in The Veterinary record, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.
- Accuracy of Tests for Diagnosis of Animal Tuberculosis: Moving Away from the Golden Calf (and towards Bayesian Models).Transboundary and emerging diseases · 2023Pooled it
- Bovine tuberculosis history as a risk factor for recurrence in English cattle herds experiencing a breakdown.The Veterinary record · 2026Article
- Prevalence and Associated Risk Factors of Bovine Tuberculosis in Dairy Cattle Determined by Comparative Intradermal Tuberculin Test in Mali and Niger, 2024.Pathogens (Basel, Switzerland) · 2026Article
- Risk Factors Influencing the Specificity of Skin Tests for Bovine Tuberculosis in a Low-Prevalence Region.International journal of veterinary science and medicine · 2026Article
- Machine learning augmented diagnostic testing to identify sources of variability in test performance.PLoS computational biology · 2025Article
- Comparative performance and age dependence of tuberculin and defined antigen bovine tuberculosis skin tests assessed with Bayesian latent class analysis.Scientific reports · 2025Article
- Integrative genomics sheds light on the immunogenetics of tuberculosis in cattle.Communications biology · 2025Article
- Difference in differences analysis evaluates the effects of the badger control policy on bovine tuberculosis in England.Scientific reports · 2024Article
- Diagnostic accuracy of the Enferplex Bovine TB antibody test using individual milk samples from cattle.PloS one · 2024Article
- The Irish bTB eradication programme: combining stakeholder engagement and research-driven policy to tackle bovine tuberculosis.Irish veterinary journal · 2023Review
- LAP-MALDI MS Profiling and Identification of Potential Biomarkers for the Detection of Bovine Tuberculosis.Journal of agricultural and food chemistry · 2023Article
- Evaluation of the performance of the IFN-γ release assay in bovine tuberculosis free herds from five European countries.Veterinary research · 2023Article
- Differences in skin test reactions to official and defined antigens in guinea pigs exposed to non-tuberculous and tuberculous bacteria.Scientific reports · 2023Article
- Performance of immunohistochemistry versus real-time PCR method for detecting mycobacterial infections of cattle screened by comparative tuberculin test.Veterinary research forum : an international quarterly journal · 2022Article
- Engaging With Farmers to Explore Correlates of Bovine Tuberculosis Risk in an Internationally Important Heritage Landscape: The Burren, in the West of Ireland.Frontiers in veterinary science · 2022Article
- Dynamics and risk of transmission of bovine tuberculosis in the emerging dairy regions of Ethiopia.Epidemiology and infection · 2021Article
- Using machine learning improves predictions of herd-level bovine tuberculosis breakdowns in Great Britain.Scientific reports · 2021Article
- Cell-Mediated Immunological Biomarkers and Their Diagnostic Application in Livestock and Wildlife Infected WithFrontiers in immunology · 2021Review
- Review
- Prevalence of Bovine Tuberculosis in Slaughtered Cattle in Sicily, Southern Italy.Animals : an open access journal from MDPI · 2020Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel method for estimating specificity of the Single Intradermal Comparative Cervical Tuberculin (SICCT) test for bovine tuberculosis (bTB) using surveillance tests results is reported. The specificity of the SICCT test at three cut-offs was estimated from the dates, locations and skinfold measurements of all routine tests carried out in Officially TB Free (OTF) cattle herds in Great Britain (GB) between 2002 and 2008, according to their separation (by distance and time) from known infected (OTF-withdrawn) herds. The proportion of animals that tested positive was constant (P>0.20) when the distance between tested herds and nearest infected herd exceeded 8 km. For standard cut-off, calculated specificity was 99.98 per cent (95 per cent confidence interval ±0.004 per cent), equating to one false positive result per 5000 uninfected animals tested. For severe cut-off it was 99.91 per cent (±0.013 per cent) and for ultrasevere cut-off (selecting all reactors and inconclusive reactors) it was 99.87 per cent (±0.017 per cent). The estimated positive predictive value of the test averaged 91 per cent and varied by regional prevalence. This study provides further evidence of the high specificity of the SICCT test under GB conditions, suggests that over 90 per cent of cattle currently culled using this test in GB were infected, and endorses slaughter of at least these cattle for bTB control.
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