ArticleScientific reports2015
Clinical characteristics of protracted bacterial bronchitis in Chinese infants.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Antibiotics for prolonged wet cough in children.The Cochrane database of systematic reviews · 2018Pooled it
- Analysis of pathogen distribution and risk factors for extended antibiotic course in children with microbiological-based protracted bacterial bronchitis in southwest China.Frontiers in pediatrics · 2026Article
- Associated Risk Factors and Diagnostic Value of Fiberoptic Bronchoscopy for Protracted Bacterial Bronchitis in Children.International journal of clinical practice · 2023Article
- Clinical features and pathogen distributions of microbiological-based protracted bacterial bronchitis in children of different ages in Northeast China.Frontiers in pediatrics · 2023Article
- Recent progress in the management of chronic cough.The Korean journal of internal medicine · 2020Review
- Update on protracted bacterial bronchitis in children.Italian journal of pediatrics · 2020Article
- When the Cough Does Not Improve: A Review on Protracted Bacterial Bronchitis in Children.Frontiers in pediatrics · 2020Review
- Wheezing in children: Approaches to diagnosis and management.International journal of pediatrics & adolescent medicine · 2019Review
- Bronchoalveolar lavage fluid microbiota dysbiosis in infants with protracted bacterial bronchitis.Journal of thoracic disease · 2018Article
- Etiologic spectrum and occurrence of coinfections in children hospitalized with community-acquired pneumonia.BMC infectious diseases · 2017Article
- ERS statement on protracted bacterial bronchitis in children.The European respiratory journal · 2017Review
- The Likelihood of Preventing Respiratory Exacerbations in Children and Adolescents with either Chronic Suppurative Lung Disease or Bronchiectasis.Frontiers in pediatrics · 2017Review
- An underestimated cause of chronic cough: The Protracted Bacterial Bronchitis.Annals of thoracic medicineReview
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Protracted bacterial bronchitis (PBB) is the common cause of chronic cough in children worldwide, but its etiology has not been fully recognized in China. We retrospectively investigated a total of 66 hospitalized infants under the age of three years with chronic wet cough enrolled in the Affiliated Children's Hospital of Soochow University from October 2010 to March 2014. All patients underwent bronchoscopy and broncho-alveolar lavage (BAL) samples were processed for microbiological and cytological analysis. Of 66 patients with wet cough, 50 (75.8%) were diagnosed with PBB. In the PBB group, wet cough was accompanied by wheezing (90%). Airway malacia were identified in 22 cases (44%). The clinical manifestations of PBB with airway malacia did not differ from those without malacia. Haemophilus influenzae (47.4%) and Streptococcus pneumoniae (36.8%) were the most commonly identified pathogens. Furthermore, CD3(+) and CD3(+)CD4(+) cells were significantly lower in the PBB group (p < 0.01), while CD19(+), CD16(+)CD56(+) and CD23(+) cells were elevated (p < 0.01) in the PBB group. Our study revealed PBB is an important cause of chronic wet cough in Chinese infants, and that changes of lymphocyte subsets are observed in children with PBB. Airway malacia frequently co-existed with PBB, but did not exacerbate the disease.
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