ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2016
Determinants of left ventricular mechanical dyssynchrony in patients submitted to myocardial perfusion imaging: A cardiac CZT study.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Mechanical dyssynchrony and diastolic dysfunction are common in LVH: a pilot correlation study using Doppler echocardiography and CZT gated-SPECT MPI.Scientific reports · 2018Trial
- Assessing the diagnostic value of left ventricular synchrony indices derived from phase analysis by D-SPECT in identifying obstructive coronary artery disease.The international journal of cardiovascular imaging · 2024Article
- Prognostic impact of cardiac resynchronization therapy guided by phase analysis: a CZT study.European heart journal. Imaging methods and practice · 2023Article
- Evaluation of dyssynchrony with nuclear cardiac imaging: New evidence for an old parameter.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Radiotherapy-Induced Cardiotoxicity: The Role of Multimodality Cardiovascular Imaging.Frontiers in cardiovascular medicine · 2022Review
- Left ventricular mechanical dyssynchrony in patient with CAD: The Saga continues.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Myocardial ischemia and previous infarction contribute to left ventricular dyssynchrony in patients with coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Demystifying dyssynchrony for diagnosis and prognosis: Tips for measuring heterogeneous phase distribution.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Incremental Value of Left Ventricular Mechanical Dyssynchrony Assessment by Nitrogen-13 Ammonia ECG-Gated PET in Patients With Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021Article
- The prognostic value of diastolic and systolic mechanical left ventricular dyssynchrony among patients with coronary artery disease and heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Electrical and mechanical dyssynchrony in patients with right bundle branch block.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- The clinical usefulness of phase analysis in detecting coronary artery disease using dipyridamole thallium-201-gated myocardial perfusion imaging with a cadmium-zinc-telluride camera.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Left ventricular mechanical dyssynchrony for CAD diagnosis: Does it have incremental clinical values?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Relationships between electrical and mechanical dyssynchrony in patients with left bundle branch block and healthy controls.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Phase dyssynchrony andJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Interactions between myocardial sympathetic denervation and left ventricular mechanical dyssynchrony: A CZT analysis.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Assessment of left ventricular mechanical dyssynchrony in coronary artery disease.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2016Article
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Abstract
backgroundAn interaction between coronary anatomy, myocardial perfusion, and left ventricular (LV) functional parameters in the development of mechanical LV dyssynchrony (LVD) has been suggested. This study examined the correlates of LVD in a large sample size of patients with known or suspected coronary artery disease (CAD) using cadmium-zinc-telluride camera.
methodsSix-hundred and fifty-seven consecutive patients who underwent myocardial perfusion imaging (MPI) and coronary angiography were included. Coronary stenosis >70% was considered significant. LV perfusion and functional parameters were computed from MPI images. The presence of significant LVD was evaluated by phase standard deviation and histogram bandwidth.
results415/657 (63%) patients had significant CAD. LVD was present in 247 (38%) patients and was associated with the presence of a higher CAD burden (P < .001), more impaired measures of LV perfusion (P < .001), contractile function (P < .001), and larger LV volumes (P < .001). By multivariate analysis, the LV end-systolic volume index (P < .001) and ischemic burden (P < .001) were the strongest predictors of LVD independent of CAD extent and LV systolic dysfunction.
conclusionsLVD is frequent in patients undergoing MPI for suspected or known CAD. Its presence is independent of CAD burden and LV systolic dysfunction, but is dependent on the presence of myocardial perfusion abnormalities and LV end-systolic volume.
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