ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2015
Attention Determines Contextual Enhancement versus Suppression in Human Primary Visual Cortex.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Distinct mechanisms of contextual modulation for dynamic natural scenes in motion- and scene-selective cortex.Journal of neurophysiology · 2026Article
- Characterizing surround suppression with dynamic natural scenes.Journal of vision · 2026Article
- Presaccadic modulation of lateral interactions.Journal of vision · 2025Article
- hMT+ activity predicts the effect of spatial attention on surround suppression.Journal of vision · 2025Article
- Altered Use of Context During Visual Perception in Psychotic Psychopathology: A Neurophysiological Investigation of Tuned and Untuned Suppression During Contrast Perception.Schizophrenia bulletin · 2024Article
- Attention preserves the selectivity of feature-tuned normalization.Journal of neurophysiology · 2023Article
- Weakened untuned gain control is associated with schizophrenia while atypical orientation-tuned suppression depends on visual acuity.Journal of vision · 2023Article
- What multiplexing means for the interpretation of functional MRI data.Frontiers in human neuroscience · 2023Article
- The specificity of orientation-tuned normalization within human early visual cortex.Journal of neurophysiology · 2021Article
- Weaker neural suppression in autism.Nature communications · 2020Article
- Normalization governs attentional modulation within human visual cortex.Nature communications · 2019Article
- Rod nuclear architecture determines contrast transmission of the retina and behavioral sensitivity in mice.eLife · 2019Article
- Article
- Characterizing the effects of feature salience and top-down attention in the early visual system.Journal of neurophysiology · 2017Article
- The effects of orientation and attention during surround suppression of small image features: A 7 Tesla fMRI study.Journal of vision · 2016Article
- Identifying separate components of surround suppression.Journal of vision · 2016Article
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Authors and funding
2 authors.
Funding
Abstract
Neural responses in primary visual cortex (V1) depend on stimulus context in seemingly complex ways. For example, responses to an oriented stimulus can be suppressed when it is flanked by iso-oriented versus orthogonally oriented stimuli but can also be enhanced when attention is directed to iso-oriented versus orthogonal flanking stimuli. Thus the exact same contextual stimulus arrangement can have completely opposite effects on neural responses-in some cases leading to orientation-tuned suppression and in other cases leading to orientation-tuned enhancement. Here we show that stimulus-based suppression and enhancement of fMRI responses in humans depends on small changes in the focus of attention and can be explained by a model that combines feature-based attention with response normalization. SIGNIFICANCE STATEMENT: Neurons in the primary visual cortex (V1) respond to stimuli within a restricted portion of the visual field, termed their "receptive field." However, neuronal responses can also be influenced by stimuli that surround a receptive field, although the nature of these contextual interactions and underlying neural mechanisms are debated. Here we show that the response in V1 to a stimulus in the same context can either be suppressed or enhanced depending on the focus of attention. We are able to explain the results using a simple computational model that combines two well established properties of visual cortical responses: response normalization and feature-based enhancement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.