SynthesisInternational journal of obesity (2005)2016
Association of overweight and obesity with patient mortality after acute myocardial infarction: a meta-analysis of prospective studies.
Synthesis in International journal of obesity (2005), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 95 citations in OpenAlex.
- The obesity paradox in ST-segment elevation myocardial infarction patients: A meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2023Pooled it
- Association Between Obesity and Cardiovascular Outcomes: Updated Evidence from Meta-analysis Studies.Current cardiology reports · 2020Pooled it
- Prognostic Implications of Coronary Microvascular Dysfunction in ST-Elevation Myocardial Infarction by Obesity Status.Diabetes, obesity & metabolism · 2026Observational
- New causal discovery algorithm over censored variables identifies subtype-specific drivers of breast cancer progression.GigaScience · 2026Article
- Evolving perspectives on evaluating obesity: from traditional methods to cutting-edge techniques.Annals of medicine · 2025Review
- The impact of body mass index on clinical outcomes in elderly sepsis patients: a retrospective study based on the MIMIC IV database.Aging clinical and experimental research · 2025Article
- The Impact of Obesity on Prostate Cancer and Progression to Castration Resistance-Real-World Data from a Romanian Center.Journal of clinical medicine · 2025Article
- The Genetic Elements of the Obesity Paradox in Atherosclerosis Identified in an Intercross Between Hyperlipidemic Mouse Strains.International journal of molecular sciences · 2025Article
- Depressive and Anxiety Symptoms, Defense Mechanisms, and Mentalized Affectivity in Individuals with Myocardial Infarction: An Empirical Investigation.Behavioral sciences (Basel, Switzerland) · 2025Article
- Impact of obesity on infarct size, circulating biomarkers, mitochondrial function and mortality in a Göttingen minipig myocardial infarct model.Lab animal · 2025Article
- Physical activity, cardiovascular disease, and mortality across obesity levels.The EPMA journal · 2025Article
- Association between BMI and cause-specific long-term mortality in acute myocardial infarction patients.American journal of preventive cardiology · 2025Article
- Assessment sleeve gastrectomy nurses' knowledge in surgical unit at Al-imam Hussein Medical city.Journal of education and health promotion · 2025Article
- Impact of the obesity paradox on 28-day mortality in elderly patients critically ill with cardiogenic shock: a retrospective cohort study.Diabetology & metabolic syndrome · 2024Article
- Body Mass Index and Outcomes in Patients with Takotsubo Syndrome: A Nationwide Retrospective Cohort Study.Cardiology · 2024Article
- Obesity paradox or hypoxia preconditioning: How obstructive sleep apnea modifies the Obesity-MI relationship.Sleep medicine · 2023Article
- Multisystem physiological perspective of human frailty and its modulation by physical activity.Physiological reviews · 2023Review
- Twelve-week high-fat diet for improving adverse ventricular remodeling post-myocardial infarction by alleviating local inflammation.Annals of translational medicine · 2022Article
- Cohort Study and Bias Analysis of the Obesity Paradox Across Stages of Chronic Kidney Disease.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2022Article
- Obesity in cases undergoing the surgical procedure of lung lobectomy: risk or benefit?Revista da Associacao Medica Brasileira (1992) · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe obesity paradox, which suggests that overweight and obesity exert protective effects on patient survival after acute myocardial infarction (AMI), is controversial in the existing researches.
objectiveThe aim of our study was to evaluate the associations of overweight and obesity with all-cause mortality in patients after AMI.
methodsThe PubMed and Embase databases were searched for original articles published in English prior to March 2015, using the terms ('myocardial infarction' and ('body mass index' or BMI)) and ('mortality' or 'death'). Prospective studies that reported the relationship between overweight and obesity at baseline (immediately after AMI) and all-cause mortality outcomes were eligible. Two authors separately performed the extraction of the data, and any differences were discussed and resolved. Pooled relative risks (RRs) and 95% confidence intervals (CIs) were computed either by fixed effects or random effects models.
resultsTwenty studies were included in the present analysis. Comparing a healthy weight group to a combined overweight and obese group, the pooled RRs were 0.72 (95% CI: 0.57-0.90) for in-hospital mortality, 0.39 (95% CI: 0.28-0.55) for short-term mortality, 0.66 (95% CI: 0.55-0.78) for medium-term mortality and 0.68 (95% CI: 0.57-0.81) for long-term mortality. However, the RRs were 0.82 (95% CI: 0.64-1.06) for in-hospital mortality and 0.94 (95% CI: 0.55-1.58) for short-term, 0.82 (95% CI: 0.65-1.04) for medium-term and 0.98 (95% CI: 0.88-1.09) for long-term mortality when the obese group was compared with the overweight group, which were not significant.
conclusionsThis meta-analysis identified an inverse association between overweight and obesity with all-cause mortality after AMI compared with healthy weight, which indicated an obesity paradox. Another notable finding is that obesity is associated with neither an increased nor a decreased risk of death in patients after AMI compared with overweight patients.
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Registered trials
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