Evidence map›Paper›PMID 26337183›Full record

ArticleJournal of endocrinological investigation2015

Quality of life and sexual function of women affected by endometriosis-associated pelvic pain when treated with dienogest.

S Caruso, M Iraci, S Cianci, E Casella, V Fava, A Cianci

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In one paragraph

Article in Journal of endocrinological investigation, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
10.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

S CarusoDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy. scaruso@unict.it.
M IraciDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy.
S CianciDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy.
E CasellaDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy.
V FavaDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy.
A CianciDepartment of General Surgery and Medical Surgical Specialties, Gynecological Clinic of the Policlinico Universitario, Via S.Sofia 78, 95124, Catania, Italy.
Policlinico Universitario di Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the study was to evaluate the effects of dienogest (DNG) on quality of life (QoL) and sexual function of women affected by endometriosis pain.

methodsFifty-four women constituted the study group and were given 2 mg/daily DNG; 48 women were given non-steroidal anti-inflammatory drugs and constitut ed the control group. To define the endometriosis-associated pelvic pain, the Visual Analogic Scale (VAS) was used. The Short Form-36 (SF-36), the Female Sexual Function Index (FSFI) and the Female Sexual Distress Scale (FSDS) were used to assess the QoL, the sexual function and the sexual distress, respectively. The study included two follow-ups at 3 and 6 months.

resultsPain improvement was observed in the study group at 3 (p < 0.05) and 6 months (p < 0.001) of treatment. At the 1st follow-up, women reported QoL improvements in some functions (p < 0.05); at the 2nd follow-up, they reported improvement in all categories (p < 0.001). The FSFI score did not change at the 1st follow-up (p = NS). On the contrary, at the 2nd follow-up, it improved with respect to the baseline (p < 0.05). At the 2nd follow-up, the FSFI score had risen to 27.8 (p < 0.001) and the FSDS score had dropped to 11.3 (p < 0.001). No change was observed in the control group (p = NS).

conclusionsThe progressive reduction of the pain syndrome reported by women over the treatment period could contribute to improve the QoL and sexual life of women on DNG.

Indexed as

Quality of LifeAdolescentAdultEndometriosisFemaleFollow-Up StudiesHormone AntagonistsHumansNandroloneOrgasmPelvic PainSexual BehaviorTreatment OutcomeYoung AdultdienogestHormone AntagonistsNandroloneChronic pelvic painDienogestDyspareuniaEndometriosisQuality of lifeSexual life

Identifiers

PMID26337183
OpenAlexW1579364324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.