Evidence map›Paper›PMID 26337078›Full record

ArticleHuman vaccines & immunotherapeutics2015

Promise of cancer stem cell vaccine.

Li Zhou, Lin Lu, Max S Wicha, Alfred E Chang, Jian-chuan Xia, Xiubao Ren, Qiao Li

Open access · bronzeAbstract read
In one paragraph

Article in Human vaccines & immunotherapeutics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  11. Dendritic cells based immunotherapy.American journal of cancer research · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

Li Zhoua Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Lin Lua Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Max S Wichaa Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Alfred E Changa Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Jian-chuan Xiac State Key Laboratory of Oncology in Southern China and Department of Experimental Research ; Sun Yat-sen University Cancer Center ; Guangzhou , China.
Xiubao Renb Department of Biotherapy ; Tianjin University Cancer Institute and Hospital; National Clinical Research Center of Cancer; Key Laboratory of Cancer Immunology and Biotherapy ; Tianjin , China.
Qiao Lia Comprehensive Cancer Center; University of Michigan ; Ann Arbor , MI USA.
Comprehensive Blood & Cancer Center · USUniversity of Michigan–Ann Arbor · USSun Yat-sen University Cancer Center · CNTianjin University · CNU-M Rogel Cancer Center

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cell (DC)-based vaccines designed to target cancer stem cells (CSC) can induce significant antitumor responses via conferring host anti-CSC immunity. Our recent studies have demonstrated that CSC-DC vaccine could inhibit metastasis of primary tumors and induce humoral immune responses against cancer stem cells. This approach highlights the promise of cancer stem cell vaccine in cancer immunotherapy.

Indexed as

AnimalsAntigens, NeoplasmCancer VaccinesDendritic CellsHumansImmunotherapy, AdoptiveMiceNeoplasm MetastasisNeoplasmsNeoplastic Stem CellsAntigens, NeoplasmCancer Vaccinescancer stem cell (CSC)dendritic cells (DC)programmed death-1 (PD-1)vaccine

Identifiers

PMID26337078
PMCPMC5054775
OpenAlexW1896786872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.