Evidence map›Paper›PMID 26336835›Full record

ReviewEndocrine2016

Treating prolactinomas with dopamine agonists: always worth the gamble?

Sean Noronha, Victoria Stokes, Niki Karavitaki, Ashley Grossman

Abstract readReview
PubMed Publisher
In one paragraph

Review in Endocrine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Clinical use of [Pituitary · 2024
    Article
  8. Review
  9. Observational
  10. Pituitary · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Hyperprolactinaemia.Journal of clinical medicine · 2019
    Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sean NoronhaOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Victoria StokesOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. vickystokes22@hotmail.com.
Niki KaravitakiOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Ashley GrossmanOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.
Oxford Centre for Diabetes, Endocrinology and Metabolism · GBUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine agonists are the treatment of choice for all patients with prolactinomas. They are generally safe, effective, and well-tolerated. However, a link between their use and the development of impulse control disorders has been well recognized in the field of neurology for some time, and evidence for a similar effect in endocrine patients is emerging. This has mainly been revealed through clinical case reports, plus a small number of comparative studies of varying robustness. We review the current available literature and discuss the implications for clinical practice, in particular emphasizing the need for clinicians to be alert to these uncommon but serious adverse effects.

Indexed as

Disruptive, Impulse Control, and Conduct DisordersDopamine AgonistsHumansPituitary NeoplasmsProlactinomaTreatment OutcomeDopamine AgonistsBromocriptineCabergolineGamblingHypersexualityImpulse control

Identifiers

PMID26336835
OpenAlexW1232084036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.