Evidence map›Paper›PMID 26336492›Full record

ArticleKardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery2015

New oral anticoagulants - a practical guide.

Tomasz Ciurus, Sebastian Sobczak, Anna Cichocka-Radwan, Malgorzata Lelonek

Open access · diamondAbstract read
In one paragraph

Article in Kardiochirurgia i torakochirurgia polska = Polish journal of cardio-thoracic surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Guideline
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  12. Assessment of patients post reversal with idarucizumab.Journal of thrombosis and thrombolysis · 2018
    Article
  13. The role of oral anticoagulants in epistaxis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tomasz CiurusDepartment of Cardiology, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, Poland.
Sebastian SobczakDepartment of Cardiology, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, Poland.
Anna Cichocka-RadwanDepartment of Cardiology, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, Poland.
Malgorzata LelonekDepartment of Cardiology, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, Poland.
Medical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral direct inhibitors of thrombin and activated factor Xa are approved as new anticoagulant drugs. In contrast to vitamin K antagonists (VKA) and heparins, the new agents have single targets in the coagulation cascade and more predictable pharmacokinetics, but they lack validated and available antidotes. Unlike VKA, they do not require routine monitoring of coagulation. However, the measurement of their pharmacologic effects might be of value in selected patients. They interfere with the routine coagulation tests, which should be interpreted with caution. Specific tests exist and can be used in case of emergencies. Adequate supportive care and temporary removal of all antithrombotic agents constitute the basis for management of serious bleeding complications. The administration of coagulation factors, such as fresh frozen plasma, prothrombin complex concentrates or recombinant activated FVII, can benefit in life-threatening bleeding or emergency surgery. Specific antidotes for non-vitamin K oral anticoagulants are in clinical development. This review aims at answering in a brief and simplified manner some clinical questions.

Indexed as

anticoagulationapixabandabigatranrivaroxaban

Identifiers

PMID26336492
PMCPMC4550032
OpenAlexW1467841933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.