ArticleBMC infectious diseases2015
Integrating interdisciplinary methodologies for One Health: goat farm re-implicated as the probable source of an urban Q fever outbreak, the Netherlands, 2009.
Article in BMC infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Toward One Health: a spatial indicator system to model the facilitation of the spread of zoonotic diseases.Frontiers in public health · 2023Pooled it
- A systematic knowledge synthesis on the spatial dimensions of Q fever epidemics.Zoonoses and public health · 2019Pooled it
- Airborne geographical dispersal of Q fever from livestock holdings to human communities: a systematic review and critical appraisal of evidence.BMC infectious diseases · 2018Pooled it
- A Q Fever Outbreak on a Boer Goat Farm in South Korea: Molecular Typing and Serial Monitoring.Animals : an open access journal from MDPI · 2026Article
- A systematic review of global Q fever outbreaks.One health (Amsterdam, Netherlands) · 2024Review
- Dairy Sheep Played a Minor Role in the 2005-2010 Human Q Fever Outbreak in The Netherlands Compared to Dairy Goats.Pathogens (Basel, Switzerland) · 2021Article
- An Accessible Diagnostic Toolbox to Detect Bacterial Causes of Ovine and Caprine Abortion.Pathogens (Basel, Switzerland) · 2021Article
- Seroprevalence and risk factors of antibodies againstEpidemiology and infection · 2021Article
- Is a One Health Approach Utilized for Q Fever Control? A Comprehensive Literature Review.International journal of environmental research and public health · 2019Review
- Spread of Coxiella burnetii between dairy cattle herds in an enzootic region: modelling contributions of airborne transmission and trade.Veterinary research · 2016Article
- Climate change effects on airborne pathogenic bioaerosol concentrations: a scenario analysis.Aerobiologia · 2016Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn spring 2008, a goat farm experiencing Q fever abortions ("Farm A") was identified as the probable source of a human Q fever outbreak in a Dutch town. In 2009, a larger outbreak with 347 cases occurred in the town, despite no clinical Q fever being reported from any local farm.
methodsOur study aimed to identify the source of the 2009 outbreak by applying a combination of interdisciplinary methods, using data from several sources and sectors, to investigate seventeen farms in the area: namely, descriptive epidemiology of notified cases; collation of veterinary data regarding the seventeen farms; spatial attack rate and relative risk analyses; and GIS mapping of farms and smooth incidence of cases. We conducted further spatio-temporal analyses that integrated temporal data regarding date of onset with spatial data from an atmospheric dispersion model with the most highly suspected source at the centre.
resultsOur analyses indicated that Farm A was again the most likely source of infection, with persons living within 1 km of the farm at a 46 times larger risk of being a case compared to those living within 5-10 km. The spatio-temporal analyses demonstrated that about 60 - 65 % of the cases could be explained by aerosol transmission from Farm A assuming emission from week 9; these explained cases lived significantly closer to the farm than the unexplained cases (p = 0.004). A visit to Farm A revealed that there had been no particular changes in management during the spring/summer of 2009, nor any animal health problems around the time of parturition or at any other time during the year.
conclusionsWe conclude that the probable source of the 2009 outbreak was the same farm implicated in 2008, despite animal health indicators being absent. Veterinary and public health professionals should consider farms with past as well as current history of Q fever as potential sources of human outbreaks.
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