Evidence map›Paper›PMID 26335910›Full record

Trial reportPain2016

Internet-delivered cognitive-behavioral treatment for adolescents with chronic pain and their parents: a randomized controlled multicenter trial.

Tonya M Palermo, Emily F Law, Jessica Fales, Maggie H Bromberg, Tricia Jessen-Fiddick, Gabrielle Tai

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Pain, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 134 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
134citing papers in PubMed, 14 pooled it
42.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

134 citing papers in PubMed, 14 syntheses or guidelines pooled it, 255 citations in OpenAlex.

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  3. Efficacy of psychological interventions on sleep in children and adolescents with chronic pain: a systematic review with meta-analysis of randomized controlled trials.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
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  14. Psychosocial interventions for recurrent abdominal pain in childhood.The Cochrane database of systematic reviews · 2017
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74 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Tonya M PalermoDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA, USA Center for Child Health, Behavior, and Development, Seattle Children's Research Institute, Seattle, WA, USA Department of Psychology, Washington State University Vancouver, Vancouver, WA, USA.
Emily F Law
Jessica Fales
Maggie H Bromberg
Tricia Jessen-Fiddick
Gabrielle Tai
Seattle Children's Hospital · USUniversity of Washington · USWashington State University Vancouver · US

Funding

An internet CBT intervention for pediatric chronic pain and disabilityR01HD062538 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2010 to 2014
$2.1M
Innovations in Pediatric Pain ResearchK24HD060068 · NICHD · SEATTLE CHILDREN'S HOSPITAL · PI PALERMO, TONYA M · 2009 to 2018
$1.6M
Psychosocial and Family Risk in Pediatric Chronic MigraineK23NS089966 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI LAW, EMILY F · 2015 to 2019
$741k
NICHD NIH HHS K24 HD060068NICHD NIH HHS R01 HD062538NICHD NIH HHS R01HD062538NINDS NIH HHS K23 NS089966
6 · The paper itself

Abstract

Internet-delivered interventions are emerging as a strategy to address barriers to care for individuals with chronic pain. This is the first large multicenter randomized controlled trial of Internet-delivered cognitive-behavioral therapy (CBT) for pediatric chronic pain. Participants included were 273 adolescents (205 females and 68 males), aged 11 to 17 years with mixed chronic pain conditions and their parents, who were randomly assigned in a parallel-group design to Internet-delivered CBT (n = 138) or Internet-delivered Education (n = 135). Assessments were completed before treatment, immediately after treatment, and at 6-month follow-up. All data collection and procedures took place online. The primary analysis used linear growth models. Results demonstrated significantly greater reduction on the primary outcome of activity limitations from baseline to 6-month follow-up for Internet CBT compared with Internet education (b = -1.13, P = 0.03). On secondary outcomes, significant beneficial effects of Internet CBT were found on sleep quality (b = 0.14, P = 0.04), on reducing parent miscarried helping (b = -2.66, P = 0.007) and protective behaviors (b = -0.19, P = 0.001), and on treatment satisfaction (P values < 0.05). On exploratory outcomes, benefits of Internet CBT were found for parent-perceived impact (ie, reductions in depression, anxiety, self-blame about their adolescent's pain, and improvement in parent behavioral responses to pain). In conclusion, our Internet-delivered CBT intervention produced a number of beneficial effects on adolescent and parent outcomes, and could ultimately lead to wide dissemination of evidence-based psychological pain treatment for youth and their families.

Indexed as

AdolescentAnxietyChildChronic PainCognitive Behavioral TherapyDepressionFemaleHumansInternetMalePain ManagementParentsRemote ConsultationTreatment Outcome

Identifiers

PMID26335910
PMCPMC4852469
OpenAlexW2396217055

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.