Evidence map›Paper›PMID 26335901›Full record

SynthesisWorld journal of surgery2015

Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection: A Systematic Review.

Jiang-Ping Yu, Yong-Jun Liu, Ya-Li Tao, Rong-Wei Ruan, Zhao Cui, Shu-Wen Zhu, Wang Shi

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in World journal of surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Jiang-Ping YuDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Yong-Jun LiuDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Ya-Li TaoDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Rong-Wei RuanDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Zhao CuiDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Shu-Wen ZhuDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China.
Wang ShiDepartment of Endoscopy Center, Zhejiang Province Tumour Hospital, 38 Guangji Road, Hangzhou, 310022, Zhejiang, China. wangsh357@sina.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoscopic submucosal dissection (ESD) is rapidly becoming a favored method for removing early esophageal cancer, but the residual defects can be complicated with strictures that require repeated endoscopic balloon dilatation. Measures for preventing the post-ESD strictures have been sought. We conducted a systematic review of recent studies to evaluate these methods.

methodsWe searched MEDLINE, Cochrane Central Register of Controlled Trials, Embase, and Google Scholar until November 30, 2014. Included studies were prospective and retrospective one- and two-arm studies. All studies had to include at least on preventive method for post-ESD stricture. Thirteen studies were included in the review.

resultsAmong the studies that used corticosteroids to prevent post-ESD stricture, we found that (1) injection of triamcinolone acetonide into the esophageal lesion resulted in a substantial reduction in the rate of stricture, and (2) the use of oral prednisolone was associated with a significantly reduced rate of dilatation sessions and stricture. Studies of other preventative measures included more recently developed scaffold-based and cell-based tissue-engineering approaches which seem very promising but require additional rigorously controlled studies to test their effectiveness.

conclusionsUntil a safer and more effective method is developed, our review supports the use of corticosteroids, either through injection or oral route, together with endoscopic dilatation in prevention of post-ESD strictures.

Indexed as

Administration, OralAnti-Inflammatory AgentsDilatationDissectionEsophageal NeoplasmsEsophageal StenosisEsophagoscopyHumansInjections, IntralesionalMucous MembranePrednisoloneTissue EngineeringTriamcinolone AcetonideAnti-Inflammatory AgentsPrednisoloneTriamcinolone Acetonide

Identifiers

PMID26335901
OpenAlexW1760557727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.