Evidence map›Paper›PMID 26335822›Full record

ArticleDoklady. Biochemistry and biophysics2015

The analysis of microRNAs miR-200C and miR-145 expression in colorectal cancer of different molecular subtypes.

Y A Shelygin, V P Shubin, S A Frolov, S I Achkasov, O I Sushkov, A S Tsukanov, V N Kashnikov, N I Pospekhova

Abstract read
PubMed Publisher
In one paragraph

Article in Doklady. Biochemistry and biophysics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Y A ShelyginState Scientific Center of Coloproctology, ul. Salyama Adilya 2, Moscow, 123423, Russia.
V P Shubin
S A Frolov
S I Achkasov
O I Sushkov
A S Tsukanov
V N Kashnikov
N I Pospekhova

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The expression levels of microRNAs miR-200c and miR-145 in two groups of colorectal cancer differing by the presence/absence of epithelial-mesenchymal transition (EMF) were studied. In the EMF-positive cancer, the level of miR-145 is increased, whereas the level of miR-200c is reduced. The reverse situation is observed in the EMI-negative cancer. MiR-145 can serve as a marker of the mesenchymal subtype of cancer. Gene expression profiles and microRNAs allow prognostically unfavorable tumors of the mesenchymal subtype to be distinguished.

Indexed as

Gene Expression Regulation, NeoplasticAdultAgedAged, 80 and overColorectal NeoplasmsEpithelial-Mesenchymal TransitionFemaleHumansMaleMicroRNAsMiddle AgedMicroRNAsMIRN145 microRNA, humanMIRN200 microRNA, human

Identifiers

PMID26335822

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.