ArticleBMC complementary and alternative medicine2015
The antibacterial, phytochemicals and antioxidants evaluation of the root extracts of Hydnora africanaThunb. used as antidysenteric in Eastern Cape Province, South Africa.
Article in BMC complementary and alternative medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
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- Hydrogel for the Controlled Delivery of Bioactive Components from Extracts ofMolecules (Basel, Switzerland) · 2023Article
- Anti-helminthic effects and cellular mechanisms ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022Article
- Qualitative, Quantitative, Cytotoxic, Free Radical Scavenging, and Antimicrobial Characteristics ofMolecules (Basel, Switzerland) · 2022Article
- Bactericidal activity of some plant essential oils againstSaudi journal of biological sciences · 2022Article
- Biocontrol Approaches againstFoods (Basel, Switzerland) · 2022Review
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- Understanding the Ethnobotany, Chemistry, Pharmacology, and Distribution of GenusPlants (Basel, Switzerland) · 2021Review
- Phytochemical Profile and Antimicrobial Activities of Edible MushroomEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Phytochemical screening andHeliyon · 2020Article
- Genoprotective activities of plant natural substances in cancer and chemopreventive strategies in the context of 3P medicine.The EPMA journal · 2020Review
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- Evaluation of chemical constituents and in vitro antimicrobial, antioxidant and cytotoxicity potential of rhizome of Astilbe rivularis (Bodho-okhati), an indigenous medicinal plant from Eastern Himalayan region of India.BMC complementary and alternative medicine · 2019Article
- Physicochemical Characterization, Microbiological Quality and Safety, and Pharmacological Potential ofOxidative medicine and cellular longevity · 2018Article
- Antiulcer Activity and Potential Mechanism of Action of the Leaves ofOxidative medicine and cellular longevity · 2018Article
- The Traditional Medicine and Modern Medicine from Natural Products.Molecules (Basel, Switzerland) · 2016Review
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Abstract
backgroundTo determine the anti-dysenteric, phytochemicals and antioxidative properties of the root extracts of Hydnora africana. The use of plants for the treatment of dysentery and other diseases in traditional medicine has increased on the basis of these rich traditional medicine systems. Series of pharmacological tests are recommended since the aetiology of many diseases may be due to more than one factor.
methodsThe agar well diffusion method was used to determine the susceptibility of bacterial strains to crude extracts of the plant. The minimum inhibitory concentration was determined by the microdilution test. The presence of phytochemicals and antioxidant was also assessed using standard methods.
resultsThe antimicrobial activity of H. africana against all the tested organisms demonstrated a mean zone diameter of inhibition ranging from 0 to 25 mm. The MIC of the extracts ranged from 0.071 to 5.0 mg/mL. Antioxidant activity showed lower ferric reducing activities, moderate nitric oxide, moderate DPPH and higher ABTS scavenging activities of the plant. Phytochemical assay revealed the presence and equivalent quantity of alkaloids, tannins, flavonoids, saponins and phenolic acid in the extracts. The water and methanol extracts were also shown as the best solvents of extraction for the phytochemicals.
conclusionsThe methanol and acetone extracts of H. africana exhibited a significant antibacterial and antioxidant activities, suggesting the presence of either good bioactive potency or the high concentration of the active principle in the extracts which may serve as a guide for selecting bio- medicinal substances of plant origin in antidysenteric drugs.
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