Evidence map›Paper›PMID 26335023›Full record

ArticlePLoS neglected tropical diseases2015

New Players in the Same Old Game: Disturbance of Group 2 Innate Lymphoid Cells in HIV-1 and Mycobacterium leprae Co-infected Patients.

Pedro Henrique Papotto, Solange Maeda, Jane Tomimori, Marília Brasil Xavier, Luiz Vicente Rizzo, Esper Georges Kallas, Karina Inácio Carvalho

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Pedro Henrique PapottoHospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo, Brazil.
Solange MaedaUniversidade Federal de São Paulo, Dermatology Department, São Paulo, Brazil.
Jane TomimoriUniversidade Federal de São Paulo, Dermatology Department, São Paulo, Brazil.
Marília Brasil XavierUniversidade Federal do Pará, Dermatology Department, Pará, Brazil.
Luiz Vicente RizzoHospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo, Brazil.
Esper Georges KallasUniversidade de São Paulo, Faculdade de Medicina, Disciplina de Imunologia Clínica e Alergia (LIM60), São Paulo, Brazil.
Karina Inácio CarvalhoHospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo, Brazil.
Hospital Israelita Albert Einstein · BRUniversidade Federal de São Paulo · BRAssociação Brasileira de Alergia e Imunologia · BRUniversidade Federal do Pará · BR

Funding

PHS HHS 52731
6 · The paper itself

Abstract

Leprosy control is achieved through a fine-tuning of TH1 and TH2 immune response pattern balance. Given the increasing epidemiological overlay of HIV and M. leprae infections, immune response in co-infected patients consists in an important contemporary issue. Here we describe for the first time the innate lymphoid cells compartment in peripheral blood of leprosy and HIV/M. leprae co-infected patients, and show that co-infection increases group 2 innate lymphoid whilst decreasing group 1 innate lymphoid cells frequencies and function.

Indexed as

Immunity, InnateAdultCoinfectionFemaleHIV-1HIV InfectionsHumansLeprosyLymphocyte SubsetsMaleMiddle AgedMycobacterium lepraeYoung Adult

Identifiers

PMID26335023
PMCPMC4559394
OpenAlexW1899431256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.