ArticleAIDS research and human retroviruses2015
Physical Activity and Its Association with Insulin Resistance in Multicenter AIDS Cohort Study Men.
Article in AIDS research and human retroviruses, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- The Influence of Exercise on Cardiovascular Health in Sedentary Adults With Human Immunodeficiency Virus.The Journal of cardiovascular nursingTrial
- Physical activity interventions for cardiometabolic and psychosocial outcomes in people living with HIV in sub Saharan Africa: A systematic review.PLOS global public health · 2026Article
- Challenges to Physical Activity Participation Among Older People Living with HIV: Scoping Review.International journal of environmental research and public health · 2025Article
- Quantile regression based method for characterizing risk-specific behavioral patterns in relation to longitudinal left-censored biomarker data collected from heterogeneous populations.Journal of applied statistics · 2025Article
- Physical activity and survival in chronic comorbidity among adult HIV patients in Ethiopia: a prospective cohort study.BMC infectious diseases · 2023Article
- Characteristics and efficacy of physical activity interventions to improve cardiometabolic and psychosocial outcomes in people living with HIV in sub-Saharan Africa: a protocol for a systematic review.Systematic reviews · 2023Article
- Patterns of objectively measured physical activity differ between men living with and without HIV.AIDS (London, England) · 2022Article
- Older People Living with HIV Were Less Physically Active Than Their Uninfected Counterparts in China: A Matched-Sample Mediation Analysis.AIDS and behavior · 2022Article
- Factors Associated With Insulin Resistance in Adults With HIV Receiving Contemporary Antiretroviral Therapy: a Brief Update.Current HIV/AIDS reports · 2018Review
- Physical activity among HIV-positive patients receiving antiretroviral therapy in Hanoi and Nam Dinh, Vietnam: a cross-sectional study.BMJ open · 2018Article
- Metabolic Complications and Glucose Metabolism in HIV Infection: A Review of the Evidence.Current HIV/AIDS reports · 2016Review
- Physical activity trends and metabolic health outcomes in people living with HIV in the US, 2008-2015.Progress in cardiovascular diseasesArticle
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Authors and funding
8 authors.
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Abstract
The association between physical activity (PA), degree of insulin resistance (IR), and HIV infection is unclear. We hypothesized that PA might differentially affect the degree of IR through the direct and indirect influences of HIV, antiretroviral medications, and sociodemographic characteristics. The International Physical Activity Questionnaire (IPAQ) was administered to Multicenter AIDS Cohort Study (MACS) participants from 4/2010 to 3/2011 to generate metabolic equivalents (METs) total score and PA category. We determined the concurrent homeostatic model assessment IR (mmol/liter) (HOMA-IR) value from fasting glucose and insulin. We examined the HIV-PA relationship using quantile regression and the HIV-PA-HOMA-IR value relationship using linear regression. Among the 1,281 men, the proportions of men in the low (25% in HIV(+) vs. 23% in HIV(-)), moderate (26% vs. 27%), and high (49% vs. 49%) PA categories were similar by HIV status. The HOMA-IR value was higher among the HIV(+) men (p<0.001), and both HIV infection and low PA were associated with a higher degree of IR (p<0.0001 and p=0.0007). However, the PA-HOMA-IR value interaction was not different by HIV status. The HOMA-IR value was higher among HIV(+) men although the PA was similar. It is unknown if more exercise will overcome the metabolic derangements associated with HIV and its treatment.
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