ArticleGenetics in medicine : official journal of the American College of Medical Genetics2016
Development and preliminary evaluation of an online educational video about whole-genome sequencing for research participants, patients, and the general public.
Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Patient in Precision Medicine: A Systematic Review Examining Evaluations of Patient-Facing Materials.Journal of healthcare engineering · 2018Pooled it
- Can an Animation Improve Parents' Knowledge and How Does It Compare to Written Information? Development and Survey Evaluation of an Animation for Parents About Prenatal Sequencing.Prenatal diagnosis · 2026Trial
- The NYCKidSeq randomized controlled trial: Impact of GUÍA digitally enhanced genetic results disclosure in diverse families.American journal of human genetics · 2023Trial
- Development of a web-based, theory-guided narrative intervention for women at elevated risk for breast cancer.Patient education and counseling · 2023Trial
- Impact of patient education videos on genetic counseling outcomes after exome sequencing.Patient education and counseling · 2020Trial
- How Has the Rise of Direct-To-Consumer Genetic Testing Impacted Genetic Counselling Practice? A Scoping Review.Clinical genetics · 2026Article
- Animated videos for childhood cancer precision medicine: development and evaluation with parents and patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- "It's a Godsend": Parental experiences of genomic testing for paediatric inborn errors of immunity.European journal of human genetics : EJHG · 2025Article
- Psychological and behavioural considerations for integrating polygenic risk scores for disease into clinical practice.Nature human behaviour · 2025Review
- Promoting Health Literacy With Human-in-the-Loop Video Understandability Classification of YouTube Videos: Development and Evaluation Study.Journal of medical Internet research · 2025Article
- Patient and providers' perspectives on using the GUÍA digital tool to enhance genomic results disclosure.Genetics in medicine open · 2025Article
- Attitudes, knowledge, and risk perceptions of patients who received elective genomic testing as a clinical service.Genetics in medicine : official journal of the American College of Medical Genetics · 2024Article
- Article
- A video intervention to improve patient understanding of tumor genomic testing in patients with cancer.Cancer medicine · 2024Article
- Educational tools support informed decision-making for genetic carrier screening in a heterogenic Israeli population.Journal of community genetics · 2024Article
- Knowledge, attitudes and decision regret: a longitudinal survey study of participants offered genome sequencing in the 100,000 Genomes Project.European journal of human genetics : EJHG · 2023Article
- The TeleKidSeq pilot study: incorporating telehealth into clinical care of children from diverse backgrounds undergoing whole genome sequencing.Pilot and feasibility studies · 2023Article
- Patient Understanding of Tumor Genomic Testing: A Quality Improvement Effort.JCO oncology practice · 2023Review
- Developing video education materials for the return of genomic test results to parents and adolescents.PEC innovation · 2022Article
- Creating accessible Spanish language materials for Clinical Sequencing Evidence-Generating Research consortium genomic projects: challenges and lessons learned.Personalized medicine · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs whole-genome sequencing (WGS) increases in availability, WGS educational aids are needed for research participants, patients, and the general public. Our aim was therefore to develop an accessible and scalable WGS educational aid.
methodsWe engaged multiple stakeholders in an iterative process over a 1-year period culminating in the production of a novel 10-minute WGS educational animated video, "Whole Genome Sequencing and You" (https://goo.gl/HV8ezJ). We then presented the animated video to 281 online-survey respondents (the video-information group). There were also two comparison groups: a written-information group (n = 281) and a no-information group (n = 300).
resultsIn the video-information group, 79% reported the video was easy to understand, satisfaction scores were high (mean 4.00 on 1-5 scale, where 5 = high satisfaction), and knowledge increased significantly. There were significant differences in knowledge compared with the no-information group but few differences compared with the written-information group. Intention to receive personal results from WGS and decisional conflict in response to a hypothetical scenario did not differ between the three groups.
conclusionsThe educational animated video, "Whole Genome Sequencing and You," was well received by this sample of online-survey respondents. Further work is needed to evaluate its utility as an aid to informed decision making about WGS in other populations.Genet Med 18 5, 501-512.
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